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| 1 | Diabetes mellitus and cognitive impairments显示文摘There is strong evidence that diabetes mellitus increases the risk of cognitive impairment and dementia. Insulin signaling dysregulation and small vessel disease in the base of diabetes may be important contributing factors in Alzheimer's disease and vascular dementia pathogenesis, respectively. Optimal glycemic control in type 1 diabetes and identification of diabetic risk factors and prophylactic approach in type 2 diabetes are very important in the prevention of cognitive complications. In addition, hypoglycemic attacks in children and elderly should be avoided. Anti-diabetic medications especially Insulin may have a role in the management of cognitive dysfunction and dementia but further investigation is needed to validate these findings. | Elham Saedi Mohammad Reza Gheini Firoozeh Faiz Mohammad Ali Arami | 2016 | World Journal of Diabetes2016，7，17： | 23 |
| 2 | Macrophages are the primary effector cells in IL-7-induced arthritis显示文摘Synovial macrophages are crucial in the development of joint inflammation and bone damage;however, the pathways that controlmacrophage remodeling in inflammatory M1 cells or bone-eroding osteoclasts are not fully understood. We determined thatelevated IL-7R/CD127 expression is the hallmark of rheumatoid arthritis (RA) M1 macrophages and that these cells are highlyresponsive to interleukin-7 (IL-7)-driven osteoclastogenesis. We established that lipopolysaccharide (LPS), interferon-γ (IFNγ), andtumor necrosis factor-α (TNFα), the classic M1 macrophage mediators, enhance IL-7R expression in RA and murine macrophages.The local expression of IL-7 provokes arthritis, predominantly through escalating the number of F480^(+)iNOS^(+) cells rather than CD3^(+)T cells. Ectopic LPS injection stabilizes IL-7-induced arthritis by increasing myeloid IL-7R expression, in part via IFNγ induction.Hence, in RAG−/− mice, IL-7-mediated arthritis is suppressed because of the reduction in myeloid IL-7R expression due to the lackof IFNγ. Moreover, the amelioration of IL-7-induced arthritis by anti-TNF therapy is due to a decrease in the number of cells in theunique F480^(+)iNOS^(+)IL-7R^(+)CCL5^(+) subset, with no impact on the F480^(+)Arginase^(+) cell or CD3^(+) T cell frequency. Consistent with thepreclinical findings, the findings of a phase 4 study performed with RA patients following 6 months of anti-TNF therapy revealedthat IL-7R expression was reduced without affecting the levels of IL-7. This study shifts the paradigm by discovering that IL-7-induced arthritis is dependent on F480^(+)iNOS^(+)IL-7R^(+)CCL5^(+) cell function, which activates TH-1 cells to amplify myeloid IL-7Rexpression and disease severity. | Seung-jae Kim Huan J.Chang Michael VVolin Sadiq Umar Katrien Van Raemdonck Aimee Chevalier Karol Palasiewicz John W.Christman Suncica Volkov Shiva Arami Mehrdad Maz Anjali Mehta Ryan K.Zomorrodi David A.Fox Nadera Sweiss Shiva Shahrara | 2020 | Cellular & Molecular Immunology2020，17，7： | 4 |
| 3 | Bundles of self-assembled boehmite nanostrips from a surfactant free hydrothermal route显示文摘 | ARAMI H MAZLOUMI M KHALIFEHZADEH R SADRNEZHAAD S K | 2008 | J Alloys Compd2008，461，： | 1 |
| 4 | Electrochemical effect of cat- ionic gemini surfactant and halide saXts on corrosion inhibition of low carbon steel in acid medium显示文摘 | Asefi D Arami M Mabmoodi N M | 2010 | Corrosion Science2010，52，： | 1 |
| 5 | Investigation on the relationshipbetween diabetes mellitus type 2 and cognitive impairment显示文摘 | Ebady SA Arami MA Shafigh MH | 2008 | Diabetes Res Clin Pract2008，82，3： | 1 |
| 6 | Grafting of chitosan as a biopolymer onto wool fabric using anhydride bridge and its antibacterial property 显示文摘 | Marziyeh Ranjbar-Mohammadi Mokhtar Arami Hajir Bahrami | 2010 | Colloids and Surfaces B : Biointerfaces2010，76，： | 1 |
| 7 | Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensit stabilization of its alpha subunit显示文摘 | HUANG L E ARAMY I LIVINGSTON D M | 1996 | J Biol Chem1996，271，32： | 1 |
| 8 | Grafting of chitosan as a biopolymer onto wool fabric using anhydride bridge and its antibacterial property 显示文摘 | RANJBAR-MOHAMMADI M ARAMI M BAHRAMI H | 2010 | Colloids and Surfaces B: Biointerfaces2010，，76： | 1 |
| 9 | Evaluation of the adsorption kinet- ics and equilibrium for the potential removal of acid dyes显示文摘 | ARAMI M LINAEE N Y | 2008 | Chemieal Engineering Journal2008，139，1： | 1 |
| 10 | Reactive milling synthesis of nanocrystalline Al-Cu/Al2O3 nanocomposite 显示文摘 | Arami H Simchi A | 2007 | Materials Science and Engineering2007，464，： | 1 |
| 11 | Binary system dye removal fromcolored textile waster using activated carbon:Kinetic and isotherm studies显示文摘 | Mahmoodi N M Salehi R Arami M | 2011 | Desalination2011，272，123： | 1 |
| 12 | Removal of Mn2' ions from synthetic wastewater by electrocoagulation process 显示文摘 | Shafaei A Rezayee M Arami M | 2010 | Desalination2010，260，123： | 1 |
| 13 | Equilibrium and kinetics studies for the adsorption of direct and acid dyes from aqueous solution by soy meal hull显示文摘 | Arami M Limaee NY Mahmoodi NM etal | 2006 | Journal of Hazardous Materials2006，135，13： | 1 |
| 14 | Degumming of Persian silk with mixed proteolytic enzymes 显示文摘 | ARAMI M RAHIMI S MIVEHIE L el al | 2007 | Journal OF Applied Polymer Science2007，106，1： | 1 |
| 15 | Real-time embedded emotional controller显示文摘 | JAMALI M R DEHYADEGARI M ARAMI A | 2010 | Neural Computing and Applications2010，19，1： | 1 |
| 16 | Study on the removal of acid dyes suing chitosan as a natural coagulant/coagulant aid显示文摘 | Zonoozi M H Moghaddam M R A Arami M | 2011 | Water Science and Technol- ogy2011，63，3： | 1 |
| 17 | Hemiparkinson-ism-hemiatrophy syndrome显示文摘 | AYROMLOU H NAJMI S ARAMI MA | 2011 | Archives of Iranian Medicine2011，14，： | 1 |
| 18 | Effect of nonionic cosurfactants on corrosion inhibition effect of cationic gemini surfactant显示文摘 | Asefi D Mahmodi N M Arami M | 2010 | Colloids Surf A2010，355，123： | 1 |
| 19 | Binary system dye removal from colored textile wastewater using activated carbon:kinetic and isotherm studies显示文摘 | Mahmoodi N M Salehi R Arami M | 2011 | Desalination2011，272，1： | 1 |
| 20 | Investi-gationon the r elationship between diabetes mellitus type 2 andcognitive impairment 显示文摘 | EBADY S A ARAMI M A SHAFIGH M H | 2008 | Diabetes Res Clin Pract2008，82，9： | 1 |
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