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| 1 | Diagnosis and Treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018显示文摘There has been a long-standing need for guidelines on the diagnosis and treatment of keloids and hypertrophic scars that are based on an understanding of the pathomechanisms that underlie these skin fibrotic diseases.This is particularly true for clinicians who deal with Asian and African patients because these ethnicities are highly prone to these diseases.By contrast,Caucasians are less likely to develop keloids and hypertrophic scars,and if they do,the scars tend not to be severe.This ethnic disparity also means that countries vary in terms of their differential diagnostic algorithms.The lack of clear treatment guidelines also means that primary care physicians are currently applying a hotchpotch of treatments,with uneven outcomes.To overcome these issues,the Japan Scar Workshop(JSW)has created a tool that allows clinicians to objectively diagnose and distinguish between keloids,hypertrophic scars,and mature scars.This tool is called the JSW Scar Scale(JSS)and it involves scoring the risk factors of the individual patients and the affected areas.The tool is simple and easy to use.As a result,even physicians who are not accustomed to keloids and hypertrophic scars can easily diagnose them and judge their severity.The JSW has also established a committee that,in cooperation with outside experts in various fields,has prepared a Consensus Document on keloid and hypertrophic scar treatment guidelines.These guidelines are simple and will allow even inexperienced clinicians to choose the most appropriate treatment strategy.The Consensus Document is provided in this article.It describes(1)the diagnostic algorithm for pathological scars and how to differentiate them from clinically similar benign and malignant tumors,(2)the general treatment algorithms for keloids and hypertrophic scars at different medical facilities,(3)the rationale behind each treatment for keloids and hypertrophic scars,and(4)the body site-specific treatment protocols for these scars.We believe that this Consensus Document will be helpful for physicians from all over the world who treat keloids and hypertrophic scars. | Rei Ogawa Sadanori Akita Satoshi Akaishi Noriko Aramaki-Hattori Teruyuki Dohi Toshihiko Hayashi Kazuo Kishi Taro Kono Hajime Matsumura Gan Muneuchi Naoki Murao Munetomo Nagao Keisuke Okabe Fumiaki Shimizu Mamiko Tosa Yasuyoshi Tosa Satoko Yamawaki Shinichi Ansai Norihisa Inazu Toshiko Kamo Reiko Kazki Shigehiko Kuribayashi | 2019 | Burns & Trauma2019，7，1： | 31 |
| 2 | Gq signaling is required for allergen-induced pulmonary eosinophilia显示文摘 | Borchers M T Justice P J Ansay T | 2002 | J Immunol2002，168，7： | 2 |
| 3 | Designing heterostructured FeP–CoP for oxygen evolution reaction:Interface engineering to enhance electrocatalytic performance显示文摘It is significant to develop highly efficient electrocatalysts for energy conversion systems.Interface engineering is one of the most feasible approaches to effectively enhance the electrocatalytic activity.Herein,the density functional theory(DFT)calculations predict that the potential barriers of Fe sites at the interface of FeP–CoP heterostructures are lower than that of Fe sites in FeP nanoparticles(NPs),Co sites in CoP NPs,or Co sites in heterostructures.Motivated by the DFT calculation results,FeP–CoP heterostructures have been designed and synthesized by a metal–organic frameworks(MOFs)confined-phosphorization method.The FeP–CoP exhibits the lowest overpotential of 230 mV at the current density of 10 mA·cm^(−2)for oxygen evolution reaction(OER),compared with FeP(470 mV)and CoP(340 mV),which outperforms most of transition metal-based catalysts.The Tafel analysis of FeP–CoP heterostructures shows an improved reaction kinetic pathway with the smallest slope of 90.3 mV·dec^(−1),as compared to the Tafel slopes of FeP NPs(137 mV·dec^(−1))and CoP NPs(114 mV·dec^(−1)).And the FeP–CoP shows extraordinary long-term stability over 24 h.The excellent activity and long-term stability of FeP–CoP derive from the synergistic effect between FeP and CoP. | Shuang Hou Ansai Zhang Qi Zhou Yingjie Wen Sixie Zhang Linfeng Su Xinjie Huang Tian Wang Kun Rui Cheng Wang Huiling Liu Zhiyi Lu Peilei He | 2023 | Nano Research2023，16，5： | 2 |
| 4 | Relationship between dental caries experience of a group of Japanese Kindergarden Children and the results of two caries activity tests conductioned on their saliva and dental plaque显示文摘 | AnSai T Yamashita Shibats Y | 1994 | Int J Paediatr Dent1994，4，1： | 1 |
| 5 | Prediction of cognitive function by arterial stiffness in the very elderly 显示文摘 | Fukuhara M Matsumura K Ansai T | 2006 | Circ J2006，70，6： | 1 |
| 6 | Extraskele- tal osteochondroma arising on the plantar region 显示文摘 | Takashi Ueno Shin-inehi Ansai Tokuya Omi | 2011 | Case Rep Dermatol2011，3，2： | 1 |
| 7 | Sebaceoma and related neoplasms with sebaceous differentiation:a clinicopathologic study of 30 cases显示文摘 | Misago N Mihara I Ansai S | 2002 | Am J Dermatopathol2002，24，： | 1 |
| 8 | Immunohistochemical differentiation of extra-ocular sebaceous carcinoma from other skin cancers显示文摘 | Ansai S Mitsuhashi Y Kondo S | 2004 | J Derrnatol2004，31，12： | 1 |
| 9 | Immunohistoehemieal differentiation of extra-ocular sebaceous carcinoma from other skin cancers 显示文摘 | Ansai S Mistuhashi Y Kondo S | 2004 | J Dermatol2004，31，12： | 1 |
| 10 | Immunohistoehemieal differentiation of extra-ocular sebaceous carcinoma from other skin cancers显示文摘 | Ansai S Mitsuhashi Y Koudo S | 2004 | J Dermatol2004，31，： | 1 |
| 11 | Temporal activation of anti- and pro-apoptotic factors in human gingival fibroblasts infected with the periodontal pathogen, Porphyromonas gingivalis : poten- tial role of bacterial proteases in host signaling 显示文摘 | Urnowey S Ansai T Bitko V | 2006 | BMC Micro- biol2006，8，6： | 1 |
| 12 | LuxS-based signaling affects Streptococcus mutans biofilm formation显示文摘 | Yoshida A Ansai T Takehara T | 2005 | Applied Envi- ronment Microbiol2005，71，5： | 1 |
| 13 | Temporal activation of anti-and pro-apoptotic factors in human gingival fibroblasts infected with the periodontal pathogen,Porphyromonas gingivalis:potential role of bacterial proteases in host signalling显示文摘 | Urnowey S Ansai T Bitko V | 2006 | BMC Microbiol2006，6，： | 1 |
| 14 | Loop-mediated isothermal amplification method for the rapid detection of Enterococcus faecalis in infected root canals 显示文摘 | Kato H Yoshida A Ansai T | 2007 | Oral Microbiology and Immunology2007，22，2： | 1 |
| 15 | In vitro assessment of chemokine receptor-ligand interactions mediating mouse eosinophil migration 显示文摘 | Borchers MT Ansay T DeSalle R | 2002 | J Leukoc Biol2002，71，6： | 1 |
| 16 | Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the hacterium Prevotella intermedia 显示文摘 | Ansai T Awano S Chen X | 1998 | FEBS Lett1998，428，3： | 1 |
| 17 | Case of palisaded encapsulated neuroma involving the palm 显示文摘 | Tamura N Asayama S Ansai S | 2013 | J Dermatol2013，40，2： | 1 |
| 18 | Fatal Genital Verrucous Carcinoma显示文摘 | Shin-ichi Ansai MD Tetsunori Kimura MD and Masahiro Hayashi MD | 2007 | Am J Dermatopathol2007，29，1： | 1 |
| 19 | Temporal activation of anti-and pro-apoptotic factors in human gingival fibroblasts infected with the periodontal pathogen,Porphyromonas gingivalis:potential role of bacterial proteases in host signaling显示文摘 | Urnowey S Ansai T Bitko V | 2006 | BMC Microbiol2006，6，： | 1 |
| 20 | Loop-mediated isothermal amplification method for the rapid detection of En- terococcus faecalis in infected root canals显示文摘 | Kato H Yoshida A Ansai T | 2007 | Oral Microbiology and Immunology2007，22，2： | 1 |
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