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| 1 | Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response显示文摘混乱毛细管扩张变异(ATM ) 调停由控制导致照耀的 foci 形成,房间周期检查点,和 apoptosis 的 DNA 损坏反应。然而,在上游的发信号怎么调整 ATM,完全没被理解。这里,我们证明在照耀刺激之上, ATM 与联系并且在 DNA 双海滨裂缝的地点在 Tyr370 (Y370 ) 是由表皮的生长因素受体(EGFR ) 的 phosphorylated。内长的 EGFR 的弄空损害调停 ATM 的 foci 形成,相应再结合,和 DNA 修理。而且,有一个 EGFR kinase 禁止者, gefitinib,块 EGFR 和 ATM 协会的预告的处理,妨碍 CHK2 激活和随后的 foci 形成,和增加放射敏感度。因此,我们揭示 EGFR 直接在 DNA 损坏反应由调整 ATM 激活的批评机制,并且我们的结果建议 ATM Y370 phosphorylation 的地位有潜力用作 biomarker 成层为独自一个的任何一个放射疗法或在有 EGFR 抑制的联合的病人。 | Hong-Jen Lee Li Lan Guang Peng Wei-Chao Chang Ming-Chuan Hsu Ying-Nai Wang Chien-Chia Cheng Leizhen Wei Satoshi Nakajima Shih-Shin Chang Hsin-Wei Liao Chung-Hsuan Chen Martin Lavin K Kian Ang Shiaw-Yih Lin Mien-Chie Hung | 2015 | Cell Research2015，25，2： | 4 |
| 2 | 勃起功能障碍患者中心血流动力学对心血管事件的预测作用显示文摘本研究调查中心血流动力学是否能够超越传统危险因素预测勃起功能障碍(erectile dysfunction,ED)患者主要不良心血管事件(major adverse cardiovascular events,MACE)的发生。方法:分析398例(平均年龄56年)ED但无确诊的心血管病患者的MACE与主动脉压和增强指数(augmentation index,AIx)之间的关系。 | Vlachopoulos C Ioakeimidis N Rokkas K Angelis A Terentes-Printzios D Kratiras Z Georgakopoulos C Tousoulis D 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，12： | 3 |
| 3 | A Review of Synergistic Effect of Photocatalysis and Ozonation on Wastewater Treatment 显示文摘 | Agustina T E Ang H M Vareek V K | 2005 | J Photo- ehem Photobiol C2005，6，4： | 1 |
| 4 | Supervised pseudo self-evolving cerebellar algorithm for generating fuzzy membership functions 显示文摘 | Ang K K Quek C | 2012 | Ex- pert Systems with Applications2012，39，3： | 1 |
| 5 | The prevalence of dementia three months after stroke and its risk factors 显示文摘 | Narasimhalu K Ang S De Silva DA | 2011 | Stroke2011，42，4： | 1 |
| 6 | Measuring environmental per- formance under different environmental DEA technologies 显示文摘 | ZHOU P ANG B W POH K L | 2008 | En- ergy Economics2008，30，1： | 1 |
| 7 | Decomposition of Aggregate Energy and Gas Emission Intensities for Industry:a Refined Divisia Index Method显示文摘 | Ang B W K H Choi | 1997 | The Energy Journal1997，18，3： | 1 |
| 8 | Solution-gated epitaxial grap- hene as pH sensor显示文摘 | ANG P K CHEN W WEE A T S et ai | 2008 | Joumal of the Am- eriean Chemical Society2008，130，14： | 1 |
| 9 | Optimum dietary protein requirement of a Malaysian freshwater catfish,Mystus nemurus显示文摘 | Khan M S Ang K J Kohl H G | 1993 | Aquaculture1993，112，： | 1 |
| 10 | A survey of data envelop-ment analysis in energy and environmental studies显示文摘 | ZHOU P ANG B W POH K L | 2008 | Euro-pean Journal of Operational Research2008，189，1： | 1 |
| 11 | Factorizing Changes in Energy and Environmental Indicators Through Decomposition 显示文摘 | ANG B W ZHANG F Q CHOI K H | 1998 | En- ergy1998，23，6： | 1 |
| 12 | Mutual infor- mation-based selection of optimal spatial-temporal patterns for single-trial EEG-based BCIs显示文摘 | Ang K K Chin Z Y Zhang H | 2012 | Pattern Recognition2012，45，6： | 1 |
| 13 | Seismic damage analysis of reinforced concrete buildings 显示文摘 | PARK Y J ANG H S WEN Y K | 1985 | Journal of Structural Engineering1985，111，4： | 1 |
| 14 | Factorizing changes in energy and environmental indicators through decompo- sition 显示文摘 | ANG B W ZHANG F Q CHOI K H | 1998 | Energy1998，23，6： | 1 |
| 15 | Lifeline response to spa- tially variable ground motion 显示文摘 | Zerva A Ang A S H Wen Y K | 1988 | Earthquake Engineering and Structural Dynamics1988，16，3： | 1 |
| 16 | Combined experimental and DFT--TD--DFT computational study of photoelectrochemical cell ru--thenium sensitizers显示文摘 | Mohammad K Nazeeruddin Filippo De Angelis Simona Fantacci | 2005 | J Am Chem Soc2005，127，16： | 1 |
| 17 | Mathematical modeling of three-dimensional flow through an asymmetric arterial stenosis 显示文摘 | Ang K C Mazumdar J N | 1997 | Math Comput Modelling1997，25，1： | 1 |
| 18 | Litter quality and decomposition in a COs-enriched Mediterranean forest ecosystem显示文摘 | DE ANGELIS P CHIGWEREWE K S MUGNOZZA G E S | 2000 | Plant and soil2000，224，： | 1 |
| 19 | Muhipactor dis- charge on metals and dielectrics: historical review and recent theories 显示文摘 | K!SHEK R A LAU Y Y ANG L K | 1998 | Physics of Plasmas1998，5，5： | 1 |
| 20 | The histone variant mac- roI-I2A1 marks repressed autosomal chromatin,but protects a subset of its target genes from silencing显示文摘 | Gamble M J Frizzell K M ~ang C | 2010 | Genes & Development2010，24，1： | 1 |
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