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| 1 | The epididymal immune balance:a key to preserving male fertility显示文摘Up to 15%of male in fertility has an immuno logical origi n,either due to repetitive infections or to autoimmune resp on ses mainly affecting the epididymis,prostate,and testis.Clinical observations and epidemiological data clearly contradict the idea that the testis confers immune protection to the whole male genital tract.As a consequenee,the epididymis,in which posttesticular spermatozoa mature and are stored,has raised some in terest in recent years when it comes to its immune mecha nisms.In deed,sperm cells are produced at puberty,long after the establishment of self-toleranee,and they possess unique surface proteins that cannot be recognized as self.These are potential targets of the immune system,with the risk of inducing autoantibodies and consequently male infertility.Epididymal immunity is based on a finely tuned equilibrium between efficient immune responses to pathogens and strong tolerance to sperm cells.These processes rely on incompletely described molecules and cell types.This review compiles recent studies focusing on the immune cell types populating the epididymis,and proposes hypothetical models of the organization of epididymal immunity with a special emphasis on the immune response,while also discussing important aspects of the epididymal immune regulation such as tolerance and tumour control. | Allison Voisin Fabrice Saez Joel R Drevet Rachel Guiton | 2019 | Asian Journal of Andrology2019，21，6： | 4 |
| 2 | 人参减少 γ射线照射的淋巴细胞微核量(英文)显示文摘目的 评价中国人参对减少辐射诱导的人周围血 G0 期淋巴细胞 (PBL)微核量的作用。方法 采用细胞因子阻滞的微核法检测健康志愿者的血标本。体外 1 37Cs照射之前 ,每份血标本的单个核细胞培养以不同浓度 (0~ 2 0 0 0μg· m l- 1 )的人参根水提取物孵育 2 4 h。结果 (1)在 0 Gy时 ,每 10 0 0个双核 (BN )细胞的微核量是 11.3± 2 .7,人参水提取物≥ 5 0 0μg· ml- 1 时微核量下降 ,但微核量和人参水提取物的浓度之间的差异是显著的。 (2 )单独射线照射显著增加微核量 ,当暴露于 1Gy的照射时 ,随着培养介质中人参水提取物浓度的增加 ,微核量呈显著的线性降低 (R2 =0 .0 5 ,P =0 .0 0 2 ) ;对暴露于 1Gy辐射诱导的微核量 ,人参水提取物浓度在 15 0 0μg· m l- 1 时减少 4 6 .6 % ,浓度在 2 0 0 0μg·m l- 1时减少 5 7.6 % ;对暴露于 2 Gy辐射诱导的微核量的减少呈更强的线性相关 (R2 =0 .7,P=0 .0 0 0 1) ;(3)微核数据分析的结果呈现出与 Poisson模型相关的过度离散趋势。结果表明 :(1)人参水提取物浓度达 2 0 0 0 μg· ml- 1时 ,对 PBL 细胞毒作用无明显影响 ;(2 )人参水提取物浓度在 5 0 0 μg· ml- 1和 2 0 0 0 μg· ml- 1之间时 ,对抗 1 37Cs照射诱导的 MN发挥保护作用。 | 李同光 Ron R Allison Kevin F O'Brien Prabhaker G Khazanie Larry J Dobbs Jr. Peter J Kragel | 2004 | 新乡医学院学报2004，21，3： | 3 |
| 3 | Accuracy of biometric formulae for intraocular lens power calculation in a teaching hospital显示文摘AIM: To evaluate the accuracy of three commonly used biometric formulae across different axial lengths(ALs) at one United States Veterans Affairs teaching hospital.METHODS: A retrospective chart review was conducted from November 2013 to May 2018. One eye of each patient who underwent cataract surgery with a monofocal intraocular lens(IOL) was included. The range of postoperative follow-up period was from 3 wk to 4 mo. The Holladay 2, Barrett Universal II, and Hill-Radial Basis Function(Hill-RBF) formulae were used to predict the postoperative refraction for all cataract surgeries. For each formula, we calculated the prediction errors [including mean absolute prediction error(MAE)] and the percentage of eyes within ±0.25 diopter(D) and ±0.5 D of predicted refraction. We performed subgroup analyses for short(AL<22.0 mm), medium(AL 22.0-25.0 mm), and long eyes(AL>25.0 mm).RESULTS: A total of 1131 patients were screened, and 909 met the inclusion criteria. Resident ophthalmologists were the primary surgeons in 710(78.1%) cases. We found no statistically significant difference in predictive accuracy among the three formulae over the entire AL range or in the short, medium, and long eye subgroups. Across the entire AL range, the Hill-RBF formula resulted in the lowest MAE(0.384 D) and the highest percentage of eyes with postoperative refraction within ±0.25 D(42.7%) and ±0.5 D(75.5%) of predicted. All three formulae had the highest MAEs(>0.5 D) and lowest percentage within ±0.5 D of predicted refraction(<55%) in short eyes.CONCLUSION: In cataract surgery patients at our teaching hospital, three commonly used biometric formulae demonstrate similar refractive accuracy across all ALs. Short eyes pose the greatest challenge to predicting postoperative refractive error. | Kevin S Tang Elaine M Tran Allison J Chen David R Rivera Jorge J Rivera Paul B Greenberg | 2020 | International Journal of Ophthalmology(English edition)2020，13，1： | 3 |
| 4 | Photo- sensitizer in clinical PDT显示文摘 | ALLISON R R DOWNIE G H ROSA C | 2004 | Photodiagnosis and Photo- dynamic Therapy2004，，1： | 1 |
| 5 | Introductory to the ESPEN guidelines in enteral nutrition: terminology, definitions and general topics显示文摘 | Lochs H Allison SP Meier R | 2006 | Clin Nutr2006，25，2： | 1 |
| 6 | Resonance response of scanning force mi- croscopy cantilevers显示文摘 | Chen G Y Warmack R J Thundat T Allison D P Huang A | 1994 | Review of Scientific Instru-ment1994，65，8： | 1 |
| 7 | Thermal and ambient-induceddeflections of scanning force microscope cantilevers显示文摘 | Thundat T Warmack R J Chen O Y Allison D P | 1994 | Applied Physics Let- ters1994，64，21： | 1 |
| 8 | Valuable patents 显示文摘 | Allison J R Lemley M A Moore K A | 2004 | Georgetown Law Journal2004，92，3： | 1 |
| 9 | Measuring health inequality using qualitative data显示文摘 | ALLISON R A FOSTER J E | 2004 | Journal of Health Economics2004，23，2： | 1 |
| 10 | Elevated enzyme activities in soils under the invasive nitrogen-fixing tree falcataria moluccana显示文摘 | Allison S D Nielsen C Hughes R F | 2006 | Soil Biology & Biochemistry2006，38，7： | 1 |
| 11 | Annual Deaths Attributable to Obesity in the United States显示文摘 | ALLISON D B FONTAINE K R MANSON J E | 1999 | JAMA1999，282，： | 1 |
| 12 | Valuable patents显示文摘 | Allison J R Lemley M A Moore K A | 2004 | Georgetown Law Journal2004，92，： | 1 |
| 13 | Transport and transformation of dissolved and particulate materials on conti- nental margins influenced by major rivers: benthic boundary layer and seabed processes 显示文摘 | Mekee B A Aller R C Allison M A | 2004 | Continental Shelf Research2004，24，78： | 1 |
| 14 | Pulsed dye laser treatment of bum scars: alleviation or iiTitation显示文摘 | Allison K P Kiernan M N Waters R A | 2003 | ? Burns2003，29，： | 1 |
| 15 | Preparation of Cr-doped Y3Al5O12 phosphors by heterogeneous precipitation methods and their luminescent properties显示文摘 | MATSUBARA I PARANTHAMAN M ALLISON S W CATES M R BESHEARS D L HOLCOMB D E | 2000 | Materials Research Bulletin2000，35，2： | 1 |
| 16 | Brain-computer interface systems: Progress and prospects显示文摘 | Allison B Z Wolpaw E W Wolpaw J R | 2007 | Expert Re- view of Medical Devices2007，4，4： | 1 |
| 17 | Introductory to the ESPEN Guide- lines on Enteral Nutrition: Terminology, definitions and general topics显示文摘 | H Lochs Allison SP Meier R | 2006 | Clin Nutr2006，25，2： | 1 |
| 18 | Annual deaths Attributable to Obesity in the United Kingdom显示文摘 | Allison D B Fontaine K R Manson J E | 1999 | The Journal of American Medical Association1999，，282： | 1 |
| 19 | Patterns in nutrient availability and plant diversity of temperate north America wetlands显示文摘 | BEDFORD L B WALBRIDGE M R ALLISON A | 1999 | Ecology1999，80，7： | 1 |
| 20 | Annual Dealths Attributable to Obesity in the United States显示文摘 | Allison D B Fontaine K R Manson J E | 1999 | Jama1999，，282： | 1 |
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