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| 1 | 人参减少 γ射线照射的淋巴细胞微核量(英文)显示文摘目的 评价中国人参对减少辐射诱导的人周围血 G0 期淋巴细胞 (PBL)微核量的作用。方法 采用细胞因子阻滞的微核法检测健康志愿者的血标本。体外 1 37Cs照射之前 ,每份血标本的单个核细胞培养以不同浓度 (0~ 2 0 0 0μg· m l- 1 )的人参根水提取物孵育 2 4 h。结果 (1)在 0 Gy时 ,每 10 0 0个双核 (BN )细胞的微核量是 11.3± 2 .7,人参水提取物≥ 5 0 0μg· ml- 1 时微核量下降 ,但微核量和人参水提取物的浓度之间的差异是显著的。 (2 )单独射线照射显著增加微核量 ,当暴露于 1Gy的照射时 ,随着培养介质中人参水提取物浓度的增加 ,微核量呈显著的线性降低 (R2 =0 .0 5 ,P =0 .0 0 2 ) ;对暴露于 1Gy辐射诱导的微核量 ,人参水提取物浓度在 15 0 0μg· m l- 1 时减少 4 6 .6 % ,浓度在 2 0 0 0μg·m l- 1时减少 5 7.6 % ;对暴露于 2 Gy辐射诱导的微核量的减少呈更强的线性相关 (R2 =0 .7,P=0 .0 0 0 1) ;(3)微核数据分析的结果呈现出与 Poisson模型相关的过度离散趋势。结果表明 :(1)人参水提取物浓度达 2 0 0 0 μg· ml- 1时 ,对 PBL 细胞毒作用无明显影响 ;(2 )人参水提取物浓度在 5 0 0 μg· ml- 1和 2 0 0 0 μg· ml- 1之间时 ,对抗 1 37Cs照射诱导的 MN发挥保护作用。 | 李同光 Ron R Allison Kevin F O'Brien Prabhaker G Khazanie Larry J Dobbs Jr. Peter J Kragel | 2004 | 新乡医学院学报2004，21，3： | 3 |
| 2 | Blood classical monocytes phenotype is not altered in primary non-small cell lung cancer显示文摘AIM: To evaluate the M1 and M2 monocyte phenotype in patients with non-small cell lung cancer(NSCLC) compared to controls. Also, to examine the expression of Th1 and Th2 cytokines in plasma of NSCLC vs controls. METHODS: Freshly prepared peripheral blood mononuclear cells samples were obtained from patients with NSCLC(lung adenocarcinoma and squamous cell lung carcinoma) and from non-cancer controls. Flow cytometry was performed to investigate M1 and M2 phenotypes in peripheral monocytes(classical monocytes CD14+, CD45+ and CD16-) using conventional surface markers. Th1 and Th2 cytokine production was alsoanalysed in the plasma using cytometric bead array technique. RESULTS: There were no significant difference in expression of M1(HLA-DR) and/or M2 markers(CD163 and CD36) markers on classical monocytes in patients with NSCLC compared to non-cancer controls. Expression of CD11 b, CD11 c, CD71 and CD44 was also shown to be similar in patients with NSCLC compared to noncancer controls. Th1 and Th2 cytokines [interleukin(IL)-1β, IL-2, IL-4, IL-5, IL-8, IL-10, IL-12(p70), tumor necrosis factor(TNF)-α, TNF-β, and interferon-γ] analysis revealed no significant difference between patients with NSCLC and non-cancer controls. CONCLUSION: This study shows no alteration in peripheral monocyte phenotype in circulating classical monocytes in patients with NSCLC compared to noncancer controls. No difference in Th1 and Th2 cytokine levels were noted in the plasma of these patients. | Saleh A Almatroodi Christine F Mc Donald Allison L Collins I an A Darby Dodie S Pouniotis | 2014 | World Journal of Clinical Oncology2014，5，5： | 2 |
| 3 | Infrared spectroscopic studies of lyophilization-and temperature- induced protein aggregation显示文摘 | A Dong S J Prestrelski S D Allison J F Carpenter | 1995 | J Pharm Sci1995，84，： | 1 |
| 4 | Nonsteroidal anti-inflammatory drugs and cardiovascular outcomes in women: results from the women's health initiative 显示文摘 | Barry AA Thomas F Allison M | 2014 | Circ Cardiovasc Qual Outcomes2014，7，4： | 1 |
| 5 | Elevated enzyme activities in soils under the invasive nitrogen-fixing tree falcataria moluccana显示文摘 | Allison S D Nielsen C Hughes R F | 2006 | Soil Biology & Biochemistry2006，38，7： | 1 |
| 6 | CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation显示文摘 | Krumme Allison J P | 1995 | J Immunoh1995，182，2： | 1 |
| 7 | Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis显示文摘 | SUN X ALLISON C MATrHEWS F E | 2013 | Mol Autism2013，4，1： | 1 |
| 8 | Responses of potato (Solanum tuberosum) to potassium fertilizers显示文摘 | ALLISON M F FOWLER J H ALLEN E J | 2001 | Journal of Agricultural Science Cambridge2001，136，： | 1 |
| 9 | A framework for the design of wildlife conservation corridors with specific application to southwestern Ontaro 显示文摘 | Allison M F Robert D B | 1997 | Landscapes and Urban Planning1997，，37： | 1 |
| 10 | Capsid protein and helper component-proteinase function as potyvirus cell-to-cell movement proteins 显示文摘 | Rojas M R Zerbini F M Allison R F | 1997 | Virology1997，237，2： | 1 |
| 11 | Using the sustainable liveli- hoods framework to identify constraints and opportunities to the development of freshwater prawn fanning in southwest Bangladesh 显示文摘 | Ahmed N Allison E H Muir J F | 2008 | Journal of the World Aquaculture Society2008，39，5： | 1 |
| 12 | Ammonium fixation and availability in vermiculite显示文摘 | ALLISON F E ROLLER E M JANET H D | 1953 | Soil Sci1953，75，： | 1 |
| 13 | Recombination between viral RNA and tr ansgenic plant transcripts 显示文摘 | Greene A E and Allison R F | 1994 | Science1994，263，： | 1 |
| 14 | A historical review of quality control in hematology显示文摘 | | 1983 | American Technology1983，49，： | 1 |
| 15 | Cleavage of protein prM is necessary forinfection of BHK-21 cells by tick-borne encephalitis virus 显示文摘 | Elshuber S Allison S L Heiilz F X | 2003 | J Gen Virol2003，84，： | 1 |
| 16 | Responses of potato (Solanum tuberosum) to potassium fertilizers 显示文摘 | Allison M F Fowler J H Allen E J | 2001 | Journal of Agricultural Science Cambridge2001，136，： | 1 |
| 17 | The Childhood AutismSpectrum Test ( CAST) : Sex Differences 显示文摘 | Williams J Allison C Scott F | 2008 | Journal ofAutism and Developmental Disorders2008，38，10： | 1 |
| 18 | Capsid protein and helper component-proteinase function as potyvirus cell-to-cell movement proteins 显示文摘 | Rojas M R Zerbini F M Allison R F | 1997 | Virology1997，237，： | 1 |
| 19 | Kimura's disease :two case reportsand a literature review 显示文摘 | Armstrong WB Allison G Pena F | 1998 | Ann Otol Rhinol Laryngol1998，107，12： | 1 |
| 20 | An historical review of quality control in hematology显示文摘 | Allison F S | 1993 | Am J Med T echnol1993，49，9： | 1 |
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