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1Sorafenib inhibits growth and metastasis of hepatocellular carcinoma by blocking STAT3显示文摘AIM: To investigate the inhibitory role and the underlying mechanisms of sorafenib on signal transducer and activator of transcription 3 (STAT3) activity in hepatocellular carcinoma (HCC).METHODS: Human and rat HCC cell lines were treated with sorafenib. Proliferation and STAT3 dephosphorylation were assessed. Potential molecular mechanisms of STAT3 pathway inhibition by sorafenib were evaluated. In vivo antitumor action and STAT3 inhibition were investigated in an immunocompetent orthotopic rat HCC model.RESULTS: Sorafenib decreased STAT3 phosphorylationat the tyrosine and serine residues (Y705 and S727), but did not affect Janus kinase 2 (JAK2) and phosphatase shatterproof 2 (SHP2), which is associated with growth inhibition in HCC cells. Dephosphorylation of S727 was associated with attenuated extracellular signal-regulated kinase (ERK) phosphorylation, similar to the effects of a mitogen-activated protein kinase (MEK) inhibitor U0126, suggesting that sorafenib induced S727 dephosphorylation by inhibiting MEK/ERK signaling. Meanwhile, sorafenib could also inhibit Akt phosphorylation, and both the phosphatidylinositol-3-kinase (PI3K) inhibitor LY294002 and Akt knockdown resulted in Y705 dephosphorylation, indicating that Y705 dephosphorylation by sorafenib was mediated by inhibiting the PI3K/Akt pathway. Finally, in the rat HCC model, sorafenib signifi cantly inhibited STAT3 activity, reducing tumor growth and metastasis.CONCLUSION: Sorafenib inhibits growth and metastasis of HCC in part by blocking the MEK/ERK/STAT3 and PI3K/Akt/STAT3 signaling pathways, but independent of JAK2 and SHP2 activation.Fang-Ming Gu, Quan-Lin Li, Qiang Gao, Jia-Hao Jiang, Xiao-Yong Huang, Jin-Feng Pan, Jia Fan, Jian ZhouFang-Ming Gu, Quan-Lin Li, Qiang Gao, Jia-Hao Jiang, Xiao-Yong Huang, Jin-Feng Pan, Jia Fan, Jian Zhou, Liver Cancer Institute, Zhongshan Hospital and Shanghai Medical School, Fudan University, Shanghai 200032, China Author contributions: Gu FM, Li QL and Gao Q contributed equally to this work Gu FM and Li QL performed the experi- ments and interpretation of the data and statistical analysis Zhou J and Gao Q contributed to the conception and design of the study Gu FM, Gao Q, Li QL and Zhou J wrote the manuscript Jiang JH, Huang XY, Pan JF and Fan J made substantial contri- bution to the design and conception of the study and interpreta- tion of data all authors read and approved the f inal manuscript. 2011World Journal of Gastroenterology2011,17,34:18
2Tumor size as a prognostic factor in patients with advanced gastric cancer in the lower third of the stomach显示文摘AIM: To explore the impact of tumor size on outcomes in patients with advanced gastric cancer in the lower third of the stomach. METHODS: We retrospectively analyzed the clinical records of 430 patients with advanced gastric cancer in the lower third of the stomach who underwent distal subtotal gastrectomy and D2 lymphadenectomy in our hospital from January 1998 to June 2004. Receiver-operating characteristic (ROC) curve analysis was used to determine the appropriate cutoff value for tumor size, which was measured as maximum tumor diameter. Based on this cutoff value, patients were divided into two groups: those with large-sized tumors (LSTs) and those with small-sized tumors (SSTs). The correlations between other clinicopathologic factors and tumor size were investigated, and the 5-year overall survival (OS) rate was compared between the two groups. Potential prognostic factors were evaluated by univariate KaplanMeier survival analysis and multivariate Cox's propor-tional hazard model analysis. The 5-year OS rates in the two groups were compared according to pT stage and pN stage. RESULTS: The 5-year OS rate in the 430 patients with advanced gastric cancer in the lower third of the stomach was 53.7%. The mean ± SD tumor size was 4.9 ± 1.9 cm, and the median tumor size was 5.0 cm. ROC analysis indicated that the sensitivity and specificity results for the appropriate tumor size cutoff value of 4.8 cm were 80.0% and 68.2%, respectively (AUC=0.795, 95%CI: 0.751-0.839, P=0.000). Using this cutoff value, 222 patients (51.6%) had LSTs (tumor size ≥ 4.8 cm) and 208 (48.4%) had SSTs (tumor size<4.8 cm). Tumor size was significantly correlated with histological type (P=0.039), Borrmann type (P=0.000), depth of tumor invasion (P=0.000), lymph node metastasis (P=0.000), tumor-nodes metastasis stage (P=0.000), mean number of metastatic lymph nodes (P=0.000) and metastatic lymph node ratio (P=0.000). Patients with LSTs had a significantly lower 5-year OS rate than those with SSTs (37.1% vs 63.3%, P=0.000). Univariate analysis showed that depth of tumor invasion (c 2=69.581, P=0.000), lymph node metastasis (c 2=138.815, P=0.000), tumor size (c 2=78.184, P=0.000) and metastatic lymph node ratio (c 2=139.034, P=0.000) were significantly associated with 5-year OS rate. Multivariate analysis revealed that depth of tumor invasion (P=0.000), lymph node metastasis (P=0.019) and tumor size (P=0.000) were independent prognostic factors. Gastric cancers were divided into 12 subgroups: pT2N0; pT2N1; pT2N2; pT2N3; pT3N0; pT3N1; pT3N2; pT3N3; pT4aN0; pT4aN1; pT4aN2; and pT4aN3. In patients with pT2-3N3 stage tumors and patients with pT4a stage tumors, 5-year OS rates were significantly lower for LSTs than for SSTs (P<0.05 each), but there were no significant differences in the 5-year OS rates in LST and SST patients with pT23N0-2 stage tumors (P > 0.05). CONCLUSION: Using a tumor size cutoff value of 4.8cm, tumor size is a prognostic factor in patients with pN3 stage or pT4a stage advanced gastric cancer located in the lower third of the stomach.Hong-Mei Wang, Chang-Ming Huang, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Department of Gastric Surgery, Affiliated Union Hospital of Fujian Medical University, Fuzhou 350001, Fujian Province, China Author contributions: Wang HM and Huang CM conceived of the study, analyzed the data, and drafted the manuscript Zheng CH, Li P and Xie JW helped revise the manuscript critically for important intellectual content Wang JB, Lin JX and Lu J helped collect data and design the study and all authors read and approved the final manuscript. 2012World Journal of Gastroenterology2012,18,38:15
3慢性再生障碍性贫血的中医药治疗及用药经验谈显示文摘邀请中华中医药学会内科血液病专业委员会的专家教授 ,讨论慢性再生障碍性贫血的中医辨治方法与用药经验。专家们提出 ,本病病机为肾精亏损、脾失健运、脏气失调、瘀阻髓络、热毒内伏和湿浊蕴结 ,治疗以补肾健脾、益髓生血、抑肝泻火、活血化瘀、利湿化浊、清热养阴、凉血止血为主。Hematopathy Committee of All China Chinese Medicine Association 2002上海中医药杂志2002,36,10:15
4Mobile Ubiquitous Service Environment显示文摘The Mobile Ubiquitous Service Environment (MUSE),established through the coordination and integration of mobile telecommunications and ubiquitous network,in the pursuit of Always Best Experience (ABE),represents the major development trend for the next generation mobile wireless network. Research on MUSE will involve the integration of the computing model system,service platform system,operating system and terminal structure system,all of which involve exploration and innovation of a new networking structure,its control and management as well as way of measuring. The change in network resources triggers the change in network computing models. To let readers have a basic understanding of MUSE,this lecture introduces it in four sections. This section focuses on the development and demand analysis of the service platform.Zhang Ping,Ji Yang,Feng Zhiyong (Research Center for Wireless New Technology,Beijing University of Posts and Telecommunications,Beijing 100876,China) The Mobile Ubiquitous Service Environment (MUSE),established through the coordination and integration of mobile telecommunications and ubiquitous network,in the pursuit of Always Best Experience (ABE),represents the major development trend for the next generation mobile wireless network. Research on MUSE will involve the integration of the computing model system,service platform system,operating system and terminal structure system,all of which involve exploration and innovation of a new networking structure,its control and management as well as way of measuring. The change in network resources triggers the change in network computing models. To let readers have a basic understanding of MUSE,this lecture introduces it in four sections. This section focuses on the development and demand analysis of the service platform. 2007ZTE Communications2007,5,2:10
5Mosque layout desisn: An analytical study of mosque layouts in the early Ottoman period显示文摘Faris All Mustafa Ahmad Sanusi Hassan 2013Frontiers of Architectural Research2013,2,4:7
6Effect of BMI on outcomes of surgical treatment for tibial plateau fractures: A comparative retrospective case series study显示文摘Yasar Mahsut Dincel All Oner Yavuz Arikan Sever Caglar Rasit Ozcafer Mehmet Akif Gulec 2018Chinese Journal of Traumatology2018,21,2:7
7Quantum phase transition and entanglement in Li atom system显示文摘By use of the exact diagonalization method, the quantum phase transition and en- tanglement in a 6-Li atom system are studied. It is found that entanglement appears before the quantum phase transition and disappears after it in this exactly solvable quantum system. The present results show that the von Neumann entropy, as a measure of entanglement, may reveal the quantum phase transition in this model.SI LiMing1 & HOU JiXuan2 1 Department of Electronic Engineering, School of Information Science and Technology, Beijing Institute of Technology, Beijing 100081, China 2 Laboratoire de Chimie, UMR 5182 CNRS, Ecole Normale Supérieure de Lyon, 46, Allée d’Italie, F-69364 Lyon Cedex 07, France 2008Science China(Physics,Mechanics & Astronomy)2008,51,11:6
8Epidemiological characteristics of fatal pedestrian ac- cidents in Fars Province of Iran: a community-based survey显示文摘ObjectiveTo 决定在 Iran.MethodsThis 代表性的学习的 Fars 省的致命的步行事故的流行病学的特征从 2009 年 3 月在一个 29 月的时期期间在伊朗的 Fars 省被进行到 2011 年 7 月。数据从 Fars 法庭的药登记。在 4 923 记录道路交通事故死亡, 971 死亡由于步行事故。人口统计、事故相关的信息被社会科学统计套装软体版本 11.5 分析。不到 0.05 被认为死者的 significant.ResultsThe 平均数年龄的 P 价值是(47.2 ±26.2 ) 年,从 6 个月到 103 岁。男性们说明了 69.8% 所有死亡。致命的事故在 9 月是很普通的;56.1% 致命的损害发生在 intracity 道路上并且 33.1% 在 extracity 道路上。致命的头损害在 60.54% 盒子中是在场的。损害地点的评估和死亡的原因发现他们显著地与年龄被联系,在损害和死亡之间的间隔。而且,道路的类型在 mortality.ConclusionAlthough 起了一个重要作用损伤病人的临床的管理在最近的十年在我们的国家被改进了,减少损害的负担在损伤系统组织之中需要协作。Payam Peymani Seyed Taghi Heydari Amin Hoseinzadeh Yaser Safikhani Arya Hedjazi Mohammad Zarenezhad Ghasem Moafian Mohammad Reza Aghabeigi Najmeh Maharlouei All Foroutan Seyed Mehdi Ahmadi FariborzGhaffarpasand Hassan Joulaei Kamran B Lankarani 2012Chinese Journal of Traumatology2012,15,5:5
9Daily variation of urban heat island effect and its correlations to urban greenery: A case study of Adelaide显示文摘All Soitani Ehsan Sharifi 2017Frontiers of Architectural Research2017,6,4:4
10Predictors for perioperative blood transfusion in elderly patients with extra capsular hip fractures treated with cephalo-medullary nailing显示文摘我们的学习的 PurposeThe 目的是在老病人为 perioperative 输血决定预兆的因素和要求,额外的胶囊的新潮的破裂与 cephalo 髓的 device.MethodsSeventy 对待 -- 有与 cephalo 髓的钉对待的额外的胶囊的新潮的破裂的九个病人在学习被包括。年龄,性别, ASA 等级,外科,外科手术前、手术后的血色素,一些医院停留,骨折类型,输的单位的数字和 30 天的死亡预定 recorded.ResultsThe 平均数年龄是 82.3 年。47 个病人经历了一根短钉子和 32 个病人一根长钉子;53.4% 病人手术后地要求了输血。输送在71.8%长钉子被要求( p ?? 0.05 ) 。一些在非输送组的医院停留是 13 天,在输送,组是 19 天(p ?? 0.05 ) 。在需要输血的病人的三十天的死亡是5%,在非输送,组是3.7%( p ?>? 0.05 ) .ConclusionPatient 年龄, ASA 等级,钉子的外科手术前的血色素和长度是为在在与cephalo髓的钉对待的老病人的额外的胶囊的新潮的破裂的 perioperative 输血的可靠预言者并且增强一条选择输送政策。M, All Fazal Caroline Bagley Parag Garg 2018Chinese Journal of Traumatology2018,21,1:4
11Design and optimization of solid rocket motor Finocyl grain using simulated annealing显示文摘The research effort outlined the application of a computer aided design(CAD)-centric technique to the design and optimization of solid rocket motor Finocyl(fin in cylinder) grain using simulated annealing.The proper method for constructing the grain configuration model,ballistic performance and optimizer integration for analysis was presented.Finocyl is a complex grain configuration,requiring thirteen variables to define the geometry.The large number of variables not only complicates the geometrical construction but also optimization process.CAD representation encapsulates all of the geometric entities pertinent to the grain design in a parametric way,allowing manipulation of grain entity(web),performing regression and automating geometrical data calculations.Robustness to avoid local minima and efficient capacity to explore design space makes simulated annealing an attractive choice as optimizer.It is demonstrated with a constrained optimization of Finocyl grain geometry for homogeneous,isotropic propellant,uniform regression,and a quasi-steady,bulk mode internal ballistics model that maximizes average thrust for required deviations from neutrality.All Kamran LIANG Guo-zhu 2011航空动力学报2011,26,4:4
12欧、美、亚一些国家体育测验制度与健身计划综述(摘要)显示文摘通过对国外健身计划综述比较研究,得出各国政府都很重视增强国民体质的研究工作,并关注体育与社会活动的联系。各国制订的健身计划目的明确,都是服从于本国政治、经济在不同时期的发展以及民众健康的需要的。各国体育测验制度经不断修订,已日趋完善。各国的健康计划或措施,均把体育健身活动作为预防疾病、增强国民健康水平的重要内容之一。Information research group of 'healthy plan for all in China' written by Yao Yuwu 1994天津体育学院学报1994,9,2:4
13New Development of China-Russia-India Triangle显示文摘Since 2001, positive improvement has occurred in the trianglerelationship between China, Russia and India. The foreignministers of the three nations met in Russia recently, symbolizingthe launching of substantive triangular cooperation.Ma Jiali is Research Professor at CICIR. He specializes in South Asian security, especially in India’s foreign policy. He is the author of three books, such as Pay Close Attention to India: A Rising Power which is very influential. He was one of the delegates for Track Two Dialogue between China and India for all of four rounds and a delegate for Track Two Dialogue between China, Russia and India. He is also a member of Eminent Persons Group Forum between China and India. 2005Contemporary International Relations2005,15,7:4
14Inhibition of hypoxia-inducible factor 1 with acriflavine sensitizes hypoxic tumor cells to photodynamic therapy with zinc phthalocyanine-encapsulating cationic liposomes显示文摘光力学的治疗(太平洋夏季时间) 是 tumorlocalized photosensitizer 与光是激动的一种肿瘤治疗在形式,它导致反应的氧种类,肿瘤 vasculature 的破坏,肿瘤组织缺氧,肿瘤房间死亡,和反肿瘤免疫者回答的正式就职的本地生产。然而,先存在肿瘤组织缺氧可以减少肿瘤到由激活组织缺氧可诱导的因素的太平洋夏季时间 1 (HIF-1 ) 幸存小径。因此,我们与吖啶黄(ACF ) 假设了 HIF-1 的那抑制将在人的表皮状的癌(A431 ) 加重房间死亡房间。A431 肿瘤房间的太平洋夏季时间用包含 photosensitizer 锌酞毒(ZnPC ) 的最新发达并且优化的 PEGylated cationic liposomes 被执行。分子的停靠表明 ACF 绑在 HIF-1 的 dimerization 领域,并且共焦的显微镜学在组织缺氧下面从 cytosol 证实了 ACF 的 translocation 到原子核。HIF-1 在 hypoxic,然而并非 normoxic 被稳定, A431 房间列在后面太平洋夏季时间。有 ACF 的 HIF-1 的抑制在 hypoxic 条件下面增加了导致太平洋夏季时间的房间死亡的程度并且减少了 HIF-1 目标基因 VEGF, PTGS2,和 EDN1 的表示。而且,在包含 ZnPC liposomes 的水的核心的 ACF 的合作封装在比得上非包含的 ACF 的太平洋夏季时间功效上产出辅助效果。在结论, HIF-1 与 liposomal ZnPC 贡献 A431 肿瘤房间幸存追随者太平洋夏季时间。HIF-1 与的抑制免费或 liposomal ACF 改进太平洋夏季时间功效。Mans Broekgaarden Ruud Weijer Massis Krekorian Bas van den IJssel Milan Kos Lindy K. Alles Albert C. van Wijk1 Zsolt Bikadi Eszter Hazai Thomas M. van Gulik Michal Heger 2016Nano Research2016,9,6:4
15Mechanisms and molecular approaches for heat tolerance in rice (Oryza sativa L.) under climate change scenario显示文摘Rice, a staple cereal crop in many parts of the world, has been confronted with multiple environmental stresses including high temperature, negatively impacts the booting as well as anthesis growth stages. The situation is further complicated by the changing climatic conditions, resulting in gradual escalation of temperature as well as changing the rainfall pattern and frequency, thus raising a concern of food security worldwide. The situation can be combat by developing rice varieties with excellent genetics with improved morpho-physiological, biochemical, and molecular mechanisms, together can minimize the adverse effects of heat stress. Here, several strategies(encompassing genetic and genomic, and mechanisms involved) for mitigating the impact of high temperature on rice have been discussed. Finally, the utilization of genomic knowledge in augmenting the conventional breeding approaches have been comprehensively elaborated to develop heat tolerant germplasm.Syed Adeel Zafar Amjad Hameed Muhammad Amjad Nawaz MA Wei Mehmood All Noor Muzammil Hussain Mehboob-ur-Rahman 2018Journal of Integrative Agriculture2018,17,4:4
16Association of core promoter mutations of hepatitis B virus and viral load is different in HBeAg(+) and HBeAg(-) patients显示文摘AIM:To identify the prevalence of hepatitis B e antigen (HBeAg) and to assess the association of hepatitis B virus (HBV) core promoter mutations and viral load in Indonesian patients.METHODS:Sixty-four patients with chronic hepatitis,65 with liver cirrhosis and 50 with hepatocellular carcinoma were included in this study.HBeAg and hepatitis B e antibody (HBeAb) tests were performed using enzyme-linked immunosorbent assay and the mutations were analyzed by sequencing.Viral load was measured by real-time polymerase chain reaction.RESULTS:Of 179 patients,108 (60.3%) were HBeAg(-) and 86 (79.6%) of these HBeAg(-) patients had been seroconverted.The A1896 mutation was not found in HBeAg(+) patients,however,this mutation was detected in 70.7% of HBeAg(-) patients.This mutation was frequently found when HBeAg was not expressed (87.7%),compared to that found in HBeAg seroconverted patients (65.1%).The A1899 mutation was also more prevalent in HBeAg(-) than in HBeAg(+) patients (P=0.004).The T1762/A1764 mutation was frequently found in both HBeAg(+) and HBeAg(-) patients,however,the prevalence of this mutation did not significantly differ among the two groups (P=0.054).In HBeAg(+) patients,the T1762/A1764 mutation was correlated with lower HBV DNA (P < 0.001).The A1899 mutation did not correlate with HBV DNA (P=0.609).In HBeAg(-) patients,the T1762/A1764 mutation alone was not correlated with HBV DNA (P=0.095),however,the presence of either the T1762/A1764 or A1896 mutations was associated with increased HBV DNA (P < 0.001).CONCLUSION:The percentage of HBeAg(-) patients is high in Indonesia,and most of the HBeAg(-) patients had been seroconverted.The A1896 mutation was most likely the major cause of HBeAg loss.The T1762/A1764 mutation alone was associated with lower viral loads in HBeAg(+) patients,but not in HBeAg(-) patients.Andi Utama Marlinang Diarta Siburian Sigit Purwantomo Mariana Destila Bayu Intan Tri Shinta Kurniasih Susan Tai Rino Alvani Gani Laurentius Adrianus Lesmana All Sulaiman Wenny Astuti Achwan Soewignjo Soemohardjo Arnelis Nasrul Zubir Julius Syafruddin AR Lelosutan Benyamin Lukito Tantoro Harmono 2011World Journal of Gastroenterology2011,17,6:3
17Low temperature induces oocytes p34^(cdc2) synthesis and accumulation-the acquisition of competence to resume meiosis in toad oocytes显示文摘Full grown oocytes derived from Bufo Bufo gargarizans rearing at high temperature environment (24℃),never underwent GVBD after progesterone treatment. No p34cdc2, H1 kinase activity was detected in the oocytes after progesterone stimulation or OA microinjection; Western blotting analysis showed that the level of p3cdc2, and p33 in the oocytes are significantly lower than those in the oocytes derived from the hibernating toads (below 10 ℃). 25S-Met incorporation analysis showed that when the oocytes were incubated at 6℃, synthesis of about thirty defferent polypeptides was promoted or induced, including p34cdc2 and some other p13suc1-binding proteins. All these results indicated that a low temperature environment is essential for the oocytes of Bufo Bufo gargarizans to express and store some cell cycle drivers and its regulators, and to gain the maturation competence. These results will also provide a new clue for explaining the molecular mechanisms why gametogenesis of some organisms depends on a relative low temperature and how to maintain the geographical distribution of some animals.LU JI NING ZHENG GU HONG SHENG CHUANG JU LIU JIA KE TSO (Shanghai Institute of Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China)(To whom all correspondence should be addressed, present address: Shanghai Institute of Planned Parenthood 1996Cell Research1996,6,2:3
18Influence of preoperative coronary collateral circulation on in-hospital mortality in patients undergoing coronary artery bypass graft surgery with intra-aortic balloon pump support显示文摘Hasan Gungor Cemil Zencir Abraham Samuel Babu Cagdas Akgullu Ufuk Eryilmaz All Zorlu Mithat Selvi Sevil Onay Tunay Kurtoglu 2014Chinese Medical Journal2014,,17:3
19Antimicrobial Agents from Selected Medicinal Plants in Libya显示文摘Objective:To test the in vitro antimicrobial efficacy of water and methanol extracts of 23 plan species that are commonly used in Libyan folk medicine.Methods:The antimicrobial activity was determinec using the well-diffusion method.Four test microorganisms were used namely,Escherichia coli,Salmonella species,Staphylococcus aureus and Bacillus subtilis.The minimum inhibitory concentration(MIC) was determined for the high biologically active crude plant extracts.Results:Among 23 medicinal plants used in the study,only 5 methanolic extracts[Rosmarinus offcinalis L,Carduus marianium L.,Lantana camara L.,Rhus tripartite(ueria) Grande,and Thymus capitatus(L.) Hoffm(link)]showed the highest antimicrobial activity againsl Staphylococcus aureus,Bacillus subtilis and Salmonella species,while 22 methanolic and aqueous extracts showed moderate to weak antimicrobial activity on all tested organisms.However 19 of the extracts showed no activity at all against Gram-ve and Gram +ve microorganisms.MIC was found to be 1.25 mg/mL(Thymus capitatus),3 mg/mL(Rhus tripartite),4 mg/mL(Carduus marianium),5 mg/mL(Rosamarinus officinalis) and5 mg/mL(Lantana camara),respectively.Conclnsions:The present results revealed that,crude methanolic extracts of the investigated Libyan folk medicinal plants exhibited mild to high in vitro antibacterial activities against Gram-positive and Gram-negative microorganisms.Hasan MH Muhaisen Miftah Mailoud Ab-Mous Fadel A Ddeeb Aboclaid All Rtemi Omer M Taba Mehtab Parveen 2016Chinese Journal of Integrative Medicine2016,22,3:2
20Some Physical Properties of CuTlSe Alloy显示文摘The structure and optical properties of Cu0.1Tl2Se3 alloy was studied. X-ray analysis showed that the polycrystalline powder consists of a mixture of two phases Cu3jTlSe2 (monoclinic) and TISe (tetragonal). Chalcopyrite phase CuTISe2 can be obtained by annealing the powder at 250’C for 1 h. Thin film with a monoclinic phase of Cu3TlSe2 was obtained for the thick film (0.7 um). The optical parameters a, n, k, e’ and e' and the energy gap were calculated. The thermoelectric power measurements showed that S has a positive polarity over the whole range of temperature.A.Abdel All Physics Department, Faculty of Science , Helwan University, Cairo, Egypt K.A.Sharaf Physics Department, Faculty of Science, Al-Azhar University for Girls, Cairo, Egypt A.Elshafie Physics Department, Faculty of Science, Menoufia University, She 2001Journal of Materials Science & Technology2001,17,2:2
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