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| 1 | Probabilistic routing in intermittently connected networks显示文摘 | Anders Lindgren Avri Doria Olov Schelén | 2003 | ACM SIGMOBILE Mobile Computing and Communications Review2003，，3： | 4 |
| 2 | Fatty liver disease,an emerging etiology of hepatocellular carcinoma in Argentina显示文摘AIM To investigate any changing trends in the etiologies of hepatocellular carcinoma(HCC) in Argentina during the last years. METHODS A longitudinal cohort study was conducted by 14 regional hospitals starting in 2009 through 2016. All adult patients with newly diagnosed HCC either with pathology or imaging criteria were included. Patients were classified as presenting non-alcoholic fatty liver disease(NAFLD) either by histology or clinically, provided that all other etiologies of liver disease were ruled out, fatty liver was present on abdominal ultrasound and alcohol consumption was excluded. Complete follow-up was assessed in all included subjects since the date of HCC diagnosis until death or last medical visit.RESULTS A total of 708 consecutive adults with HCC were included. Six out of 14 hospitals were liver transplant centers(n = 484). The prevalence of diabetes mellitus was 27.7%. Overall, HCV was the main cause of liver disease related with HCC(37%) including cirrhotic and non-cirrhotic patients, followed by alcoholic liver disease 20.8%, NAFLD 11.4%, cryptogenic 9.6%, HBV 5.4% infection, cholestatic disease and autoimmune hepatitis 2.2%, and other causes 9.9%. A 6-fold increase in the percentage corresponding to NAFLDHCC was detected when the starting year, i.e., 2009 was compared to the last one, i.e., 2015(4.3% vs 25.6%; P < 0.0001). Accordingly, a higher prevalence of diabetes mellitus was present in NAFLD-HCC group 61.7% when compared to other than NAFLD-HCC 23.3%(P < 0.0001). Lower median AFP values at HCC diagnosis were observed between NAFLD-HCC and non-NAFLD groups(6.6 ng/m L vs 26 ng/m L; P = 0.02). Neither NAFLD nor other HCC etiologies were associated with higher mortality.CONCLUSION The growing incidence of NAFLD-HCC documented in the United States and Europe is also observed in Argentina, a confirmation with important Public Health implications. | Federico Pinero Josefina Pages Sebastián Marciano Nora Fernández Jorge Silva Margarita Anders Alina Zerega Ezequiel Ridruejo Beatriz Ameigeiras Claudia D’Amico Luis Gaite Carla Bermúdez Manuel Cobos Carlos Rosales Gustavo Romero Lucas McCormack Virginia Reggiardo Luis Colombato Adrián Gadano Marcelo Silva | 2018 | World Journal of Hepatology2018，10，1： | 4 |
| 3 | Intermediate-advanced hepatocellular carcinoma in Argentina:Treatment and survival analysis显示文摘BACKGROUND Hepatocellular carcinoma(HCC) represents the sixteenth most frequent cancer in Argentina. The rise of new therapeutic modalities in intermediate-advanced HCC opens up a new paradigm for the treatment of HCC.AIM To describe real-life treatments performed in patients with intermediateadvanced HCC before the approval of new systemic options.METHODS This longitudinal observational cohort study was conducted between 2009 and2016 in 14 different regional hospitals from Argentina. Included subjects had intermediate-advanced Barcelona Clinic Liver Cancer(BCLC) HCC stages(BCLC B to D). Primary end point analyzed was survival, which was assessed for each BCLC stage from the date of treatment until last patient follow-up or death.Kaplan Meier survival curves and Cox regression analysis were performed, with hazard ratios(HR) calculations and 95% confidence intervals(95%CI).RESULTS From 327 HCC patients, 41% were BCLC stage B, 20% stage C and 39% stage D.Corresponding median survival were 15 mo(IQR 5-26 mo), 5 mo(IQR 2-13 mo)and 3 mo(IQR 1-13 mo)(P < 0.0001), respectively. Among BCLC-B patients(n =135), 57% received TACE with a median number of 2 sessions(IQR 1-3 sessions).Survival was significantly better in BCLC-B patients treated with TACE HR =0.29(CI: 0.21-0.40) than those without TACE. After tumor reassessment by RECIST 1.1 criteria following the first TACE, patients with complete response achieved longer survival (HR = 0.15(CI: 0.04-0.56, P = 0.005))Eighty-two patients were treated with sorafenib, mostly BCLC-B and C(87.8%). However,12.2% were BCLC-D. Median survival with sorafenib was 4.5 mo(IQR 2.3-11.7 mo);which was lower among BCLC-D patients 3.2 mo(IQR 2.0-14.1 mo). A total of 36 BCLC-B patients presented tumor progression after TACE. In these patients,treatment with sorafenib presented better survival when compared to those patients who received sorafenib without prior TACE [HR = 0.26(CI: 0.09-0.71);P= 0.013].CONCLUSION In this real setting, our results were lower than expected. This highlights unmet needs in Argentina, prior to the introduction of new treatments for HCC. | Federico Pinero Sebastián Marciano Nora Fernández Jorge Silva Margarita Anders Alina Zerega Ezequiel Ridruejo Gustavo Romero Beatriz Ameigeiras Claudia D’Amico Luis Gaite Carla Bermúdez Virginia Reggiardo Luis Colombato Adrián Gadano Marcelo Silva | 2019 | World Journal of Gastroenterology2019，25，27： | 3 |
| 4 | Extensive reworking of Archaean crust within the Birimian terrane in Ghana as revealed by combined zircon U-Pb and Lu-Hf isotopes显示文摘Located in the southeastern parts of the BaouléMossi domain of the West African Craton,the Birimian terrane in Ghana is known to consist of predominantly juvenile crust emplaced during the Eburnean orogeny.Here we present novel coupled zircon U-Pb and Lu-Hf isotope data from nine Birimian granitoids intruding different domains from northwestern,western and southeastern Ghana.Sub-chondriticε_(Hf)-values indicating reworking of Archaean crust are recorded in zircon from both northwestern and southeastern Ghana.As a conservative estimate 71%of all analysed zircon grains spanning in age from2220 Ma to 2130 Ma require contribution from a reworked Archaean source,contradicting the common belief that the Birimian terrane consist of predominantly juvenile crust.A minimumε_(Hf)-value of-10.5 at2139 Ma suggests a Palaeoarchaean to late Mseoarchaean component as the contributing ancient source.Combined with previously reported heavy zirconδ^(18)O signatures from Birimian river zircon in Ghana,our new data suggests reworking of Archaean aged sediments during subduction initiated crustal growth in the vicinity of one,or possibly in between two Archaean aged cratons. | Andreas Petersson Anders Scherstén Axel Gerdes | 2018 | Geoscience Frontiers2018，9，1： | 3 |
| 5 | Interleukin-17 Family Members and Inflammation显示文摘 | Jay K. Kolls Anders Lindén | 2004 | Immunity2004，，4： | 3 |
| 6 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 7 | Hepatic and extrahepatic malignancies in primary sclerosing cholangitis显示文摘 | Annika Bergquist Anders Ekbom Rolf Olsson Dan Kornfeldt Lars L??f ?ke Danielsson Rolf Hultcrantz Stefan Lindgren Hanne Prytz Hanna Sandberg-Gertzén Sven Almer Fredrik Granath Ulrika Broomé | 2002 | Journal of Hepatology2002，，3： | 2 |
| 8 | 环境污染对地下文物的威胁显示文摘上个世纪的环境污染造成了健康问题,土地和湖水的酸化以及对文化遗产的损害。不仅露天的文物受环境污染的影响,地下文物也因此遭受不测。然而到目前为止,我们对地下文物受损状况的研究相当有限,而对这个被忽视的领域给予重视是相当重要的。在此文中,我们将报道在瑞典国家文化遗产委员会得到的有关文物受损的研究结果;这些文物是来自史前墓穴中的青铜器、铁器和骨器考古物品,它们的材料仿佛受到污染的影响最大。对调查时采用的方法作了介绍,并对其它相关的研究做了简要的综述。近年来,历史文物(特别是无机材质的文物)遭受侵蚀的速度已明显加快,而文物侵蚀速度的上升主要归因于人类造成的污染。对于污染可能危及的区域,在文中将举例说明。 | Anders G.Nord Kate Tronner Einar Mattsson Gunnar Ch.Borg Inga Ullén 赵军 | 2005 | AMBIO-人类环境杂志2005，34，3： | 2 |
| 9 | Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain显示文摘 | Sara Ekmark-Lewén Anders Lewén Charlotte Israelsson Gui Lin Li Mohammad Farooque Yngve Olsson Ted Ebendal Lars Hillered | 2010 | Restorative Neurology and Neuroscience2010，，3： | 1 |
| 10 | Branchedchain amino acids increase p70S6k Phosphorylation in human skeletal muscle after resistance exercise显示文摘 | Hakan K R Anders N Tohnny N | 2004 | Physiol Endocrinol Metab2004，287，： | 1 |
| 11 | Displacement-length scaling and fault linkage 显示文摘 | Dawers N H Anders M H | 1995 | Journal of Structural Geology1995，17，5： | 1 |
| 12 | Investigation of High-Efficiency Surface-Emitting Lasers with Blazed Grating Outcouplers 显示文摘 | Mats Hagberg Anders Larsson N E | 1996 | IEEE Journal of Quantum Electronics1996，32，9： | 1 |
| 13 | Decreasing Time-Trends of Colorectal Cancer in a Large Cohort of Patients With Inflammatory Bowel Disease显示文摘 | Sverre S?derlund Lena Brandt Annika Lapidus Per Karlén Olle Brostr?m Robert L?fberg Anders Ekbom Johan Askling | 2009 | Gastroenterology2009，，5： | 1 |
| 14 | Endothelial cell loss after phaco- emulsification:relation to preoperative and intraoperative parame-ters显示文摘 | Walkow T Anders N Klebe S | 2000 | J Cataract Refract Surg2000，26，5： | 1 |
| 15 | Decreased heart rate variability may predict the progression of carotid atherosclerosis in type 2 diabetes显示文摘 | Dr. Anders Gotts?ter ?sa Rydén Ahlgren Soumia Taimour G?ran Sundkvist | 2006 | Clinical Autonomic Research2006，，3： | 1 |
| 16 | A procedure for ranking efficient units in data envelopment analysis 显示文摘 | ANDER P PETERSEN N C | 1993 | Management Science1993，39，10： | 1 |
| 17 | Global change,soil biodiversity,and nitrogen cycling in terrestrial ecosystem:three case studies显示文摘 | Anderén O Brussaard L | 1998 | Global Change Biology1998，4，： | 1 |
| 18 | Chlamydophila pneumoniae and mycoplasma pneumoniae in respiratory specimens of children with chronic lung diseases显示文摘 | Teig N Anders A Schmidt C | 2005 | Thorax2005，60，11： | 1 |
| 19 | Peribulbar anesthesia versus topical anesthesia in cataract surgery: comparison of the postoperative course 显示文摘 | Heuermann T Anders N Rieck P | 2000 | Ophthalmologe2000，97，3： | 1 |
| 20 | Neutralization of transt- hyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phos- phorylation and loss of hippoeampal neurons: support for the am- yloid hypothesis 显示文摘 | Stein T D Anders N J DeCarli C | 2004 | J Neurosci2004，24，35： | 1 |
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