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| 1 | Detection of human papillomavirus DNA in esophageal carcinoma in Greece显示文摘AIM:To detect human papillomavirus(HPV)in theesophageal mucosa and the possible relationship with esophageal cancer in Greece.METHODS:Forty-nine patients underwent esophagogastroduodenoscopy(EGD)and esophageal biopsy at a university hospital that acts as a referral center for Northern Greece.Nineteen of these patients(14 male and 5 female)had esophageal squamous cell carcinoma(ESCC)and 30(15 male and 15 female)did not have any reported esophageal malignancy.Histopathological assessment was followed by polymerase chain reaction analysis of all the samples.Patient demographic data(age,sex,and place of birth)and information regarding smoking habits,alcohol consumption or sexual habits were collected.A method of statistical interference,verification of hypotheses based on homogeneity and independentχ2 test,was used.RESULTS:From the 49 patients that underwent EGD and biopsy,19 had ESCC and 30 had normal esophageal mucosa,with a mean age of 65.2 years.Regarding the prevalence of oncogenic risk factors for esophageal carcinoma,an interesting conclusion was that 78%of the patients used tobacco and almost one-third had multiple sexual partners,whereas only 20%of the patients consumed alcohol,which was not statistically significant,when compared to the control group.In the ESCC group,the only two positive samples were among the male patients(2/14 male patients with ESCC,14.5%).No HPV was identified in the control group.The predominant HPV types identified were 11 and 31,which have a low malignancy potential.The presence of HPV DNA in the ESCC group was not statistically significant,95%confidence interval(χ2=3.292,P=0.07).CONCLUSION:This is the first relevant study in Greece,and despite the lack of statistical significance,the issue of HPV infection and ESCC does merit further investigation. | Georgios Georgantis Theodoros Syrakos Theodoros Agorastos Spiridon Miliaras Asterios Gagalis Georgios Tsoulfas Konstantinos Spanos Georgios Marakis | 2015 | World Journal of Gastroenterology2015，21，8： | 2 |
| 2 | Safety of human papillomavirus (HPV) vaccines: a review of the international experience so far 显示文摘 | Agorastos T Chatzigeorgiou K Brotherton J M | 2009 | Vaccine2009，7，52： | 1 |
| 3 | Aromatase inhibitor anastrozole for treating endometrial hyperplasia in obese postmenopausal women显示文摘 | Agorastos T Vaitsi V Pantazis K | 2005 | Eur J Obstet Gynecol Reprod Biol2005，118，2： | 1 |
| 4 | Treatment of Endometrial Hyperplasias with Gonadotropin-Releasing Hormone Agonists:Pathological,Clinical,Morphometric,and DNA-Cytometric Data显示文摘 | Agorastos T Bontis J Vakiani A | 1997 | Gynecol Oncol1997，65，1： | 1 |
| 5 | Risk factors associated with diabetic retinopathy in patients with diabetes mellitus type 2显示文摘 | Chatziralli IP Sergentanis TN Keryttopoulos P Vatkalis N Agorastos A Papazisis L | 2010 | BMC Res Notes2010，3，： | 1 |
| 6 | Glutathione-S-transferase M1 and T1 and cytochrome P1A1 genetic polymorphisms and susceptibility to cervical intraepithelial neoplasia in Greek women显示文摘 | Agorastos T Papadopoulos N Lambropoulos AF | 2007 | Eur J Cancer Prey2007，16，6： | 1 |
| 7 | Aromatase inhibitor anastrozole for treating endometrial hyperplasia in obese postmenopausal women显示文摘 | Agorastos T Vaitsi V Pantazis K | 2005 | Eur J Obstet Gynecol Reprod Biol2005，118，2： | 1 |
| 8 | Human papilloma virus testing for primary screening in woman at low risk of developing cervical cancer显示文摘 | Agorastos T Dinas K Llove B | 2005 | Gynecolgic Oncology2005，96，3： | 1 |
| 9 | Safety of hu- man papillomavirus(HPV) vaccines: a review of the international experience so far 显示文摘 | Agorastos T Chatzigeorgiou K Brotherton JM | 2009 | Vaccine2009，27，52： | 1 |
| 10 | Safety of human papillomavirus (HPV) vaccines : A review of the international experience so far 显示文摘 | Agorastos T Chatzigeorgiou K Brotherton JM | 2009 | Vaccine2009，27，52： | 1 |
| 11 | Cervical human papillomavirus infection in women attending gynaecological outpatient clinics in northern Greece显示文摘 | Agorastos T Dinas K Lloveras B | 2004 | Eur J Cancer Pre2004，13，： | 1 |
| 12 | Human papillomavirus testing for primary screening in women at low risk of developing cervical center显示文摘 | Agorastos T Dinaak L loveras B | 2005 | Gynecologic Oncology2005，96，3： | 1 |
| 13 | Conservative management of young patients with endometrial highly-differentiated adenoeareinoma 显示文摘 | Kalogiannidis I Agorastos T | 2011 | J Obstet Gynaeeol2011，31，1： | 1 |
| 14 | Human pa- pilloma virus testing for primary screening in women at low risk of developing cervical cancer the green experience显示文摘 | AGORASTOS T DIINAS K LLOVERAS B | 2005 | Gynecol Oncol2005，96，3： | 1 |
| 15 | P53 codon 72 polymorphism and risk of intra-epithelial and invasive cervical neoplasia in Creek women 显示文摘 | Agorastos T Lambropoulos A F Constantinidis T C | 2000 | Eur J Cancer Prey2000，9，2： | 1 |
| 16 | Primary ovarian angiosarcoma : review of the literature and report of a case with coexisting chylothorax显示文摘 | Vavilis D Papadopoulos N Agorastos T | 2007 | Eur J Gynaecol Oncol2007，28，4： | 1 |
| 17 | p53 codon 72 polymorphism and risk of intra-epithelial and invasive cervical neoplasia in Greek women显示文摘 | Agorastos T Lambropoulos A F Constantinidis T C | 2000 | Eur J Cancer Prey2000，9，： | 1 |
| 18 | Adenomyosis at hysterectomy: prevalenee and relationship to operative findings and reproductive and menstrual faetors显示文摘 | Vavilis D Agorastos T Tzafetas J | 1997 | Clin Exp Obstet Gyneeol1997，24，1： | 1 |
| 19 | Safety of human papillomavirus (HPV) vaccines: a review of the international experience so far 显示文摘 | Agorastos T Chatzigeorgiou K Brotherton JM | 2009 | Vaccine2009，27，52： | 1 |
| 20 | Conservative management of young patients with endometrial highly-differentiated adenocarcinoma显示文摘 | Kalogiannidis I Agorastos T | 2011 | J Obstet Gynaecol2011，31，1： | 1 |
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