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| 1 | 急性缺血性卒中患者早期处理指南:美国心脏协会/美国卒中协会对医疗专业人员的指南显示文摘背景和目的作者提供了关于成年急性缺血性卒中患者评估和治疗方面的现有证据和处理推荐的一份概述。目标读者为涉及急性缺血性卒中患者发病48h内诊治的院前诊疗人员、医生、综合医疗保健人员和医院管理者。该指南将取代先前的2007年版指南及其2009年更新版。方法著述委员会成员由美国卒中协会卒中委员会的科学声明监督委员会指定,代表各个领域的医疗专家。在形成共识的整个过程中,严格遵循美国心脏协会的利益冲突原则。委员会成员被分配给与其专业领域相关的内容,对卒中文献进行回顾,重点为前一版指南发表之后的文献,然后按照美国心脏协会卒中委员会的证据强度分级方案起草推荐意见。结果本指南的目的是减少卒中相关的残疾和死亡。本指南支持卒中医疗体系的全局性概念以及从患者识别、急救医疗服务激活、转送和分诊到急诊室和卒中单元内最初数小时诊治的卒中诊治细节。本指南讨论了早期卒中评估和一般治疗、缺血性卒中治疗、特殊干预措施,如再灌注策略以及脑复苏的一般生理学干预原则。结论由于许多推荐意见基于有限的证据,还迫切需要对急性缺血性卒中的治疗做进一步的研究。 | Edward C. Jauch Jeffrey L. Saver Harold P. Adams Askiel Bruno J.J. (Buddy) Connors Bart M. Demaerschalk Pooja Khatri Paul W. McMullan Jr, Adnan I. Qureshi Kenneth Rosenfield Phillip A. Scott Debbie R. Summers David Z. Wang Max Wintermark Howard Yonas 李海峰(译) 岳耀先(译) 王琦(译) 张贤军(译) 丁晓君(译) | 2013 | 国际脑血管病杂志2013，21，7： | 17 |
| 2 | Impaired swallowing mechanics of post radiation therapy head and neck cancer patients: A retrospective videofluoroscopic study显示文摘AIM: To determine swallowing outcomes and hyolaryngeal mechanics associated with post radiation therapy head and neck cancer(rt HNC) patients using videofluoroscopic swallow studies. METHODS: In this retrospective cohort study, video-fluoroscopic images of rt HNC patients(n = 21) were compared with age and gender matched controls(n = 21). Penetration-aspiration of the bolus and bolus residue were measured as swallowing outcome variables. Timing and displacement measurements of the anterior and posterior muscular slings elevating the hyolaryngeal complex were acquired. Coordinate data of anatomical landmarks mapping the action of the anterior muscles(suprahyoid muscles) and posterior muscles(long pharyngeal muscles) were used to calculate the distance measurements, and slice numbers were used to calculate time intervals. Canonical variate analysis with post-hoc discriminant function analysis was performed on coordinate data to determine multivariate mechanics of swallowing associated with treatment. Pharyngeal constriction ratio(PCR) was also measured to determine if weak pharyngeal constriction is associated with post radiation therapy.RESULTS: The rt HNC group was characterized by poor swallowing outcomes compared to the control group in regards to: Penetration-aspiration scale(P < 0.0001), normalized residue ratio scale(NRRS) for the valleculae(P = 0.002) and NRRS for the piriform sinuses(P = 0.003). Timing and distance measurements of the anterior muscular sling were not significantly different in the two groups, whereas for the PMS time of displacement was abbreviated(P = 0.002) and distance of excursion was reduced(P = 0.02) in the rt HNC group. A canonical variate analysis shows a significant reduction in pharyngeal mechanics in the rt HNC group(P < 0.0001). The PCR was significantly higher in the test group than the control group(P = 0.0001) indicating reduced efficiency in pharyngeal clearance. CONCLUSION: Using videofluoroscopy, this study shows rt HNC patients have worse swallowing outcomes associated with reduced hyolaryngeal mechanics and pharyngeal constriction compared with controls. | William G Pearson Jr Alisa A Davidoff Zachary M Smith Dorothy E Adams Susan E Langmore | 2016 | World Journal of Radiology2016，8，2： | 2 |
| 3 | Comparison of the effects of an angiotensin-converting enzyme inhibitor and a vasopeptidase inhibitor after myocardial infarction in the rat显示文摘 | Lapointe N Blais C Jr Adam A | 2002 | J Am Coll Cardiol2002，39，10： | 2 |
| 4 | Emergent use of anticoagulation for treatment of patients with ischemic stroke显示文摘 | | 2002 | Stroke2002，33，3： | 1 |
| 5 | Guidelines for the management of spontaneous intracerebral hemorrhage:astatement for healthcare professionals from a special writing group of the Stroke Council,American Heart Association显示文摘 | Adams HP Jr Barsan W | 1999 | Stroke1999，30，： | 1 |
| 6 | Guidelines for the early man- agement of patients with ischemie stroke : A scientific statement from the Stroke Council of the American Stroke Association 显示文摘 | Adams HP Jr Adams RJ Brott T | 2003 | Stroke2003，34，： | 1 |
| 7 | Risk stratification for in-hospi-tal mortality in acutely decompensated heart failure:classification and regression tree analysis显示文摘 | Fanarow GC Adams KF Jr Abraham WT | 2005 | JAMA2005，293，5： | 1 |
| 8 | Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association显示文摘 | Adams HP Jr Adams RJ Brott T | 2003 | Stroke2003，34，4： | 1 |
| 9 | Measurements of acute cerebral infarction: a clinical examination scale 显示文摘 | Brott T Adams H P Jr Olinger C P | 1989 | Stroke1989，20，7： | 1 |
| 10 | Guidelines for the early management of adults with ischemic stroke:a guideline from the American Heart Association/ American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups:The American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists显示文摘 | Adams HP Jr Del ZG Alberts M J | 2007 | Circulation2007，115，： | 1 |
| 11 | Alzheimer’s disease,ceramide,visfatin andNAD显示文摘 | ADAMS J D Jr | 2008 | CNS&Neurological Disorders Drug Targets2008，7，6： | 1 |
| 12 | Guidelines for the early management of adults with ischemic stroke : a guideline from the American Heart Association/American Stroke Association Stroke Coun- cil, Clinical Cardiology Council, Cardiovascular Radiology and Inter- vention Council, and the Atherosclerotic Peripheral Vascular Disease and Quality of Care Outcomes in Research Interdisciplinary Working Groups: the American Academy of Neurology affirms the value of this guideline as an educational tool for neurologists 显示文摘 | Adams H P Jr del-Zoppo G Alberts M J | 2007 | Stroke2007，38，5： | 1 |
| 13 | A multifocal electroretinograin model predicting the development of diabetic retinopathy显示文摘 | Bearse MA Jr Adams AJ Han Y Schneck ME Ng J | 2006 | Prog Retin Eye ifes2006，25，42： | 1 |
| 14 | Guidelines for the early management of adults withischemic stroke: a guideline from the American Heart Association/American Stroke Association StrokeCouncil, ClinicalCardiology Council, CardiovascularRadiology and Inter vent ion Council, and theAtherosclerotic Peripheral VascularDisease andQualityof CareOutcomeinResearchlnterdisciplinary Working Groups:the American Academy of Neurologyaffirms the value of this guideline as an educationaltool for neurologists 显示文摘 | ADAMS H P JR DEL ZOPPO G ALBER TS M J | 2007 | Stroke2007，38，： | 1 |
| 15 | A perspective onre-evaluating digoxin' s role in ihe current management ofpatients wilh chronic systolic heart failure: targeting serumconcentration lo reduce hospitalization and improve safelyprofile显示文摘 | Adams KF Jr (ihali JK Herbert PJ | 2014 | Eur J Heart Fail2014，16，5： | 1 |
| 16 | Treating patients with 'wake-up' stroke: the experience of the AbESTF- I1 trial 显示文摘 | Adams HP Jr Leira EC Tomer JC | 2008 | Stroke2008，39，12： | 1 |
| 17 | Inhibition of coronary atherosclerosis by propranolol in behaviorally predisposed monkeys fed on atherogenic diet显示文摘 | Manuck SB Adams MR | 1987 | Circulation1987，76，： | 1 |
| 18 | Total knee arthroplasty in patients with greater than 20 degrees flexion contraeture显示文摘 | Berend KR Lombardi AV Jr Adams JB | 2006 | Clin Orthop Relat Res2006，452，11： | 1 |
| 19 | Sur-rogate end points in heart failure trials显示文摘 | Gheorghiade M Adams K F Jr Gattis W A | 2003 | Am Heart J2003，145，2： | 1 |
| 20 | Measurements of acute cerebral infarction:a clinical examination scale显示文摘 | Brott T Adams HP Jr Olinger CP | 1989 | Stroke1989，20，7： | 1 |
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