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267篇 您的检索式:作者名="Abbot"
    题名 作者 年代 出处 被引量
1青光眼药物治疗的新进展显示文摘青光眼是一种多元性的视神经和视网膜病变。全世界大约有 70 0万病人因青光眼而失明。眼压升高是青光眼发病过程中的主要危险因素。本文简要地回顾目前常用的药物疗法 ,并介绍正在研发中的新降眼压药的药效和药理机制。彭玉豪 李和平 Abbot F CLARK 2003中国新药与临床杂志2003,22,8:8
2开角型青光眼降眼压药物的新靶点研究显示文摘青光眼是我国及全球主要的致盲眼病。目前开角型青光眼的治疗局限于通过降低眼压延缓视神经病变的进展。临床用于降低眼压的药物主要机制为增强葡萄膜巩膜通路的房水外流和抑制房水生成。由于青光眼眼压升高的主要原因是小梁网通路阻力上升,因此现有药物未能从根本上纠正疾病的起源和病理生理改变。本文对直接针对青光眼小梁网房水外流阻塞病理机制的新药物靶点和治疗策略进行综述,以期这些新药物靶点和策略成为治疗青光眼的突破性新方法。毛伟明 刘扬 Robert J. Wordinger Abbot F. Clark 彭玉豪 2016中华眼科杂志2016,52,6:5
3Application of Artificial Neural Networks to Rainfall Forecasting in Queensland,Australia显示文摘In this study,the application of artificial intelligence to monthly and seasonal rainfall forecasting in Queensland,Australia,was assessed by inputting recognized climate indices,monthly historical rainfall data,and atmospheric temperatures into a prototype stand-alone,dynamic,recurrent,time-delay,artificial neural network.Outputs,as monthly rainfall forecasts 3 months in advance for the period 1993 to 2009,were compared with observed rainfall data using time-series plots,root mean squared error(RMSE),and Pearson correlation coefficients.A comparison of RMSE values with forecasts generated by the Australian Bureau of Meteorology's Predictive Ocean Atmosphere Model for Australia(POAMA)-1.5 general circulation model(GCM) indicated that the prototype achieved a lower RMSE for 16 of the 17 sites compared.The application of artificial neural networks to rainfall forecasting was reviewed.The prototype design is considered preliminary,with potential for significant improvement such as inclusion of output from GCMs and experimentation with other input attributes.John ABBOT Jennifer MAROHASY 2012Advances in Atmospheric Sciences2012,29,4:4
4青光眼的视神经保护策略显示文摘彭玉豪 李和平 Abbot F.CLARK 2004中华眼科杂志2004,40,11:2
5Airbome laser hydrography in Australia 显示文摘PENNY M F ABBOT R H PHILLIPS D M 1986App Opt1986,25,13:2
6über oxals? ure-und weins? ure-bornylester显示文摘ABBOT E B MCKENZIE A ROSS J D M 1938Berichte Der Deutschen Chemischen Gesellschaft1938,71,1:1
7Coronary heart disease and atrial fibrillation: the Framingham study 显示文摘 Abbot RD Savage DD 1983Am Heart J1983,106,2:1
8The mechanism of catalytic cracking of n-alkenes on ZSM-5 zeolite显示文摘Abbot J Wojciechowski B W 1985The Canadian Journal of Chemical Engineering1985,63,3:1
9The effects of audit committee activity and independence on corporate fraud 显示文摘Abbot J L Park Y Parker S 2000Managerial Finance2000,26,11:1
10Rodent models for glaucoma retinopathy and optic neuropathy显示文摘lok-Hou Pang Abbot FC 2007J Glaucoma2007,16,5:1
11Synthesis and charac- terization of block copolymers of polyoxyethylene and polylactide with different architectures 显示文摘Mai S M Abbot A Norton D 2009Macromolecu- lar Chemistry and Physics2009,210,10:1
12Ghrelin caus es hyperpha-giaand obesity in rats显示文摘WREN A M SMALL C J ABBOT C R 2001Diabetes2001,50,11:1
13Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells 显示文摘Jordan NJ Kolios G Abbot SE 1999J Clin Invest1999,104,:1
14Catalytic reactions of branched paraffins on HY zeolite显示文摘Abbot J Wojciechowski B W 1988J Catal1988,113,2:1
15The catalytic isomerization of 1-hexene on H-ZSM-5 zeolite:The effects of a shape-selective catalyst显示文摘Abbot J Corma A Wojciechowski B W 1985Journal of Catalysis1985,92,:1
16Individual and population variation in invertebrates revealed by Inter-simple Sequenee Repeats (ISSRs) 显示文摘Abbot P 2001Journal of Inseet Seienee2001,1,8:1
17The specificity of the CDC-1994 criteria for chronic fatigue syndrome:Comparison of health status in three groups of patients who fulfill the criteria显示文摘Kennedy G Abbot NC Spence V 2004Ann-Epidemiol2004,14,2:1
18Understanding the links between conservation and development in the Bamenda Highlands,Cameroon显示文摘Abbot J Thomas D 2001World Dev2001,29,7:1
19Catalytic reactions of n-hexenes on amorphous silica-alumina显示文摘Abbot J Wojciechowski B W 1985The Canadian Journal of Chemical Engineering1985,63,5:1
20Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue 显示文摘Hunter S B Abbot K Varma V A 1995J Neuropathol Exp Neurol1995,54,:1
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