|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update显示文摘Gallbladder cancer is a malignancy of biliary tract which is infrequent in developed countries but common in some specific geographical regions of developing countries. Late diagnosis and deprived prognosis are major problems for treatment of gallbladder carcinoma. The dramatic associations of this orphan cancer with various genetic and environmental factors are responsible for its poorly defined pathogenesis. An understanding to the relationship between epidemiology, molecular genetics and pathogenesis of gallbladder cancer can add new insights to its undetermined pathophysiology. Present review article provides a recent update regarding epidemiology, pathogenesis, and molecular genetics of gallbladder cancer. We systematically reviewed published literature on gallbladder cancer from online search engine Pub Med(http://gffzz16a62c593b5540cehpqqwp9oocq9b6up5.ffgz.tsg.suse.edu.cn/pubmed). Various keywords used for retrieval of articles were Gallbladder, cancer Epidemiology, molecular genetics and bullion operators like AND, OR, NOT. Cross references were manually searched from various online search engines(http://gffzz16a62c593b5540cehpqqwp9oocq9b6up5.ffgz.tsg.suse.edu.cn/pubmed,http://gffzz141dfffa132442b5spqqwp9oocq9b6up5.ffgz.tsg.suse.edu.cn/, http://gffzz4cb95a154d71438chpqqwp9oocq9b6up5.ffgz.tsg.suse.edu.cn/home.jsp). Most of the articles published from 1982 to 2015 in peer reviewed journals have been included in this review. | Aarti Sharma Kiran Lata Sharma Annapurna Gupta Alka Yadav Ashok Kumar | 2017 | World Journal of Gastroenterology2017，23，22： | 68 |
| 2 | 浅议大学英语教学中学生跨文化交际能力的培养显示文摘大学英语教学不仅是要教给学生语言知识,培养其听说读写等应用技能,还要着力培养学生跨文化交际的能力。培养大学生跨文化交际能力的路径和方法是:利用现有教材,培养大学生的跨文化意识;在课堂教学中利用对比法、实物讲授法、任务教学法、讨论法和直观法等教学方法,以及在课外活动中,培养大学生的跨文化交际能力;教师要增强自身的跨文化意识,提高教学水平。 | 乐琼 Chauhan Ashok Kumar | 2010 | 教育探索2010，，8： | 31 |
| 3 | Novel insights into the pathophysiology of varicocele and its association with reactive oxygen species and sperm DNA fragmentation显示文摘精索静脉曲张与减少的男繁殖潜力被联系了。与在 biomolecular 技术的进展,更好理解涉及精索静脉曲张挑起的阴囊的损坏的机制是可能的。尽管机制充分还没被描述了,它是可能的是 multifactorial,当前的证据在联系精索静脉曲张的男 subfertility 的致病建议反应的氧种类(ROS ) 和结果的氧化压力(OS ) 的中央角色。过多的 ROS 与精子 DNA 破碎被联系,它可以调停与精索静脉曲张有关的差的精子功能和授精结果的临床的表明。ROS/OS 和 DNA 破碎测试有潜力与常规精液分析相比提供另外的诊断、预示的信息并且可以在单个病人指导治疗学的管理策略。 | Chak-Lam Cho Sandro C Esteves Ashok Agarwal | 2016 | Asian Journal of Andrology2016，18，2： | 30 |
| 4 | Diagnosis of Helicobacter pylori : What should be the gold standard?显示文摘Since the discovery of Helicobacter pylori(H. pylori) in 1983, numerous detection methods for the presence of the bacterium have been developed. Each one of them has been associated with advantages and disadvantages. Noninvasive tests such as serology, 13 C urea breath test(UBT) and stool antigen tests are usually preferred by the clinicians. Serology has its own limitation especially in endemic areas while 13 C UBT is technically very demanding. The stool antigen detection method, although specific, is usually associated with poor sensitivity. The 13 C UBT is believed to be specific, but with present revelation of the fact that stomach is colonized by many other urease producing bacteria makes it questionable. Histology, culture, rapid urease test and polymerase chain reaction(PCR) are the tests which are carried out on antral biopsies collected by invasive means. Histology has been proposed to be very sensitive and specific but the question is how by simply looking the morphology of the bacteria in the microscope, one can claim that the curved bacterium is exclusively H. pylori. Rapid urease test(RUT), the doctor's test, is also challenged because the presence of other urease producing bacteria in the stomach cannot be denied. Moreover, RUT has been reported with poor sensitivity specially, when density of the bacterium is low. Isolation of H. pylori is essential to investigate its growth requirements, antibiotic susceptibility testing, studying virulence factor to develop vaccine and many more explorations. It has also got several disadvantages i.e., special condition for transporting, media, incubation and few days waiting for the colonies to appear, apart from the speed essentially needed to process the specimens. Till date, majority of the microbiological laboratories in the world are not equipped and trained to isolate such fastidious bacterium. The option left is PCR methods to detect H. pylori 's DNA in gastric mucosa, gastric juice, saliva, dental plaques and environmental specimens. There are speculations for false positivity due to detection of non-pylori Helicobacters due to genetic sharing; and false negativity due to low bacterial counts and presence of PCR inhibitors. However, specimen collection, transportation and processing do not require speed and special conditions. PCR based diagnosis may be considered as gold standard by designing primers extremely specific to H. pylori and targeting at least more than one conserved genes. Similarly specificity of PCR may be improved by use of internal Primers. Further, nested PCR will take care of false negatives by countering the effect of PCR inhibitors and low bacterial counts. Therefore, nested PCR based methods if performed properly, may be proposed as gold standard test. | Saurabh Kumar Patel Chandra Bhan Pratap Ashok Kumar Jain Anil Kumar Gulati Gopal Nath | 2014 | World Journal of Gastroenterology2014，20，36： | 30 |
| 5 | Relationship between acrosin activity of human spermatozoa and oxidative stress显示文摘Aim: To study the association between seminal oxidative stress and human sperm acrosin activity.Methods: It is a prospective study consisting of 30 infertile men and 12 fertile normozoospermic volunteers. A full history, clinical examination and scrotal ultrasound were done to exclude other related factors such as smoking and varicocele. Presence of white blood cells (WBCs) in semen samples was evaluated by peroxidase staining. Lipid peroxidation in spermatozoa was induced after incubating with ferrous sulphate (4mmol/L) and sodium ascorbate (20 mmol/L). Induced peroxidation of spermatozoa was assessed by determining the production of thiobarbituric acid reactive substances (TBARS). Acrosin activity was measured using the gelatinolysis technique. The halo diameters around the sperm heads and the percentages of spermatozoa showing halo formation were evaluated. An acrosin activity index was calculated by multiplying the halo diameter by the halo formation rate. Results: A significant difference was observed in acrosin activity parameters and TBARS levels between samples with WBCs (>1×10^6/mL of ejaculate) and those without. This difference was also noted between the normozoospermic and the oligoasthenoteratozoospermic semen samples. The TBARS production by spermatozoa had a significant negativecorrelation with the acrosin activity index (r=-0.89, P<0.001). Conclusion: The presence of oxidative stress in an individual with leukocytospermia and/or abnormal semen parameters is associated with impaired sperm function as measured by its acrosin activity. (Asian J Androl 2004 Dec; 6:313-318) | Adel A.Zalata Ashraf H.Ahmed Shyam S.R.Allamaneni Frank H.Comhaire Ashok Agarwal | 2004 | Asian Journal of Andrology2004，6，4： | 27 |
| 6 | Anterior resection for rectal carcinoma-risk factors for anastomotic leaks and strictures显示文摘AIM:To determine the incidence and factors responsible for anastomotic leaks and stricture following anterior resection(AR)and its subsequent management.METHODS:Retrospective analysis of data from 108 patients with rectal carcinoma who underwent AR or low anterior resection(LAR)to identify the various preoperative,operative,and post operative factors that might have influence on anastomotic leaks and strictures.RESULTS:There were 68 males and 40 females with an average of 47 years(range 21-75 years).The median distance of the tumor from the anal verge was 8 cm(range 3-15 cm).Sixty(55.6%)patients underwent handsewn anastomosis and 48(44.4%)were stapled.The median operating time was 3.5 h(range2.0-7.5 h).Sixteen(14.6%)patients had an anastomotic leak.Among these,11 patients required reexploration and five were managed expectantly.The anastomotic leak rate was similar in patients with and without diverting stoma(8/60,13.4%with stoma and 8/48;16.7%without stoma).In 15(13.9%)patients,resection margins were positive for malignancy.Ninteen(17.6%)patients developed anastomotic strictures at a median duration of 8 mo(range 3-20 mo).Among these,15 patients were successfully managed with per-anal dilatation.On multivariate analysis,advance age(>60 years)was the only risk factor for anastomotic leak(P=0.004).On the other hand,anastomotic leak(P=0.00),mucin positive tumor(P =0.021),and lower rectal growth(P=0.011)were found as risk factors for the development of an anastomotic stricture.CONCLUSION:Advance age is a risk factor for an anastomotic leak.An anastomotic leak,a mucin-secreting tumor,and lower rectal growth predispose patients to develop anastomotic strictures. | Ashok Kumar Ram Daga Paari Vijayaragavan Anand Prakash Rajneesh Kumar Singh Anu Behari Vinay K Kapoor Rajan Saxena | 2011 | World Journal of Gastroenterology2011，17，11： | 28 |
| 7 | 氧化应激检测在男性不育临床中的应用显示文摘活性氧 (ROS)在低浓度发生可以调节正常精子功能 ,而高浓度ROS危害精子的存活力和功能。ROS产生过量与抗氧化系统损伤会发生氧化应激 (OS)。目前认为损伤OS促进了一系列男性生殖功能的病理学改变。ROS介导的精子质膜过氧化损伤 ,可以解释在高比例的不育病人中观察到的精子功能缺陷。ROS产生过多也会破坏精子核内DNA的完整性。DNA碱基对OS敏感 ,这些结构的过氧化能引起碱基修饰、DNA链断裂以及染色质交联。由过量ROS诱发的DNA损伤会加速生殖细胞凋亡过程 ,导致与男性不育相关的精子计数降低 ,以及可以解释近半个世纪以来所观察到的精液质量明显下降现象。近 10年来 ,克里夫兰临床基金会的研究组已经查明了男性不育中OS的关键作用 ;研究的主要目的是将这些重要的知识从实验室转向临床应用。我们设计的研究目标 :①理解精液中OS发生的精确机制 ;②建立准确评估OS状态的实验 ,并进行质控研究 ;③检测OS与精子核DNA损伤之间的相关性 ; | Ashok Agarwal Ramadan Abdou Saleh | 2002 | 中华男科学杂志2002，8，1： | 26 |
| 8 | Outcome of varicocele repair in men with nonobstructive azoospermia: systematic review and meta-analysis显示文摘这全身的评论的目的是评估与 nonobstructive 精子缺乏(NOA ) 在不肥沃的人修理临床的精索静脉曲张的利益。通过手术获得的精子检索率(SRR ) 和与检索阴囊的精子的使用跟随帮助繁殖技术(艺术) 的怀孕率是主要结果。第二等的结果在手术后的精液包括了可行精子的存在避免阴囊的精子检索和怀孕率(帮助并且无助) 用手术后的呼喊的精子。收集数据的电子搜索用 MEDLINE 和 EMBASE 数据库被执行直到 2015 年 4 月。十八研究在这系统的评论被包括并且说明了与 NOA 和精索静脉曲张被诊断的 468 个病人。这些病人受到也外科的精索静脉曲张修理或经皮的 embolization。评估精子检索结果的三控制研究显示在经历了 varicocelectomy 的病人,没有精索静脉曲张修理, SRR 与那些相比增加了(或:2.65;95% CI:1.69-4.14;P <0.001 ) 。尽管有阴囊的精子的使用的怀孕率赞成了 varicocelectomy 组,结果不是统计上重要的(临床的怀孕率或:2.07;95% CI:0.92-4.65;P = 0.08;实时出生率或:2.19;95% CI:0.99-4.83;P = 0.05 ) 。留下十五研究报导手术后的精液分析结果。在 43.9% 病人(变化:20.8%-55.0%) ,精子在手术后的精液被发现。怀孕率为无助、帮助(在 IVF/ICSI 以后) 分别地在有在手术后的精液的精子的人的组是 13.6% 和 18.9% 。我们的调查结果显示在有 NOA 和临床的精索静脉曲张的病人的 varicocelectomy 与改进 SRR 被联系。另外,约 44% 对待的人将有在精液的足够的精子避免精子检索。有手术后的呼喊的精子和收获阴囊的精子的怀孕结果上的有限数据预防关于在对待的个人的可能的增加的富饶潜力的任何坚挺的结论。在结论,我们的学习的结果显示有 NOA 和临床的精索静脉曲张的不肥沃的人得益于 varicocelectomy。给可得到的证据的低 / 中等的质量,医生们与精索静脉曲张的风险和好处修理的 NOA 与他们的病人讨论,是明智的。 | Sandro C Esteves Ricardo Miyaoka Matheus Roque Ashok Agarwal | 2016 | Asian Journal of Andrology2016，18，2： | 21 |
| 9 | 氧化磷酸化与糖酵解:精子以何种途径获取能量?显示文摘精子为高度特异性的细胞,提供精子重要功能的主要能源一一三磷酸腺苷(ATP)主要通过两种代谢途径形成,即糖酵解和氧化磷酸化(OXPHOS)。ATP除了在精子的头部和鞭毛的主段通过糖酵解的方式产生外,在线粒体主要通过OXPHOS的方式产生。然而,在精子成功受精的过程中主要以何种方式产生ATP具有很大的差异性。与糖酵解相比,线粒体呼吸被认为是一种更有效的ATP合成代谢过程。然而,研究表明ATP从线粒体到精子鞭毛末端的扩散电位不足以支持精子的运动,这表明糖酵解是精子尾部区域主要的获能方式。多项研究表明虽然糖酵解是鞭毛产生ATP的主要方式,但是,精子运动所需要的能量主要还是来自于线粒体的呼吸。有些研究表明当糖酵解受到抑制的时候,精子仍能维持其正常的运动和功能,虽然目前尚未明确这种运动是否能持续足够长的时间,是否能够达到有效受精。本文主要目的是对哺乳动物精子能量的代谢进行综述,分析人类精子在受精的过程中以何种ATP代谢途径作为主要的能量供应方式。 | Stefan S du Plessis Ashok Agarwal Gayatri Mohanty Michelle van der Linde | 2015 | Asian Journal of Andrology2015，17，2： | 19 |
| 10 | Outcome of assisted reproductive technology in met with treated and untreated varicocele, systematic review and meta-analysis显示文摘 | Sandro C Esteves Matheus Roque Ashok Agarwal | 2016 | Asian Journal of Andrology2016，18，2： | 19 |
| 11 | Extracts of passion fruit peel and seed of Passiflora edulis(Passifloraceae) attenuate oxidative stress in diabetic rats显示文摘This study was aimed at evaluating the anti-diabetic potential of passion fruit Passiflora edulis(EPE) extracts in diabetic rats, following Streptozotocin(STZ) induced oxidative stress. Thirty adult Wistar rats were divided into five groups, with six rats in each group. The control rats were injected intraperitoneally with citrate buffer(pH 4.5). The remaining groups of rats were administered single dose of 45 mg·kg-1 of STZ by intraperitoneal route to induce diabetes. The diabetic animals were treated with 250 and 500 mg·kg-1 of EPE and glibenclamide 0.6 mg·kg-1 for fifteen days by oral route. Blood glucose, end organ oxidative stress marker, and anti-oxidants were assayed. Further, histopathological investigation of pancreas was studied at the end of the experimentation. The results revealed that subacute administration of EPE significantly(P < 0.001) controlled the blood glucose level in the diabetic rats. In addition, EPE extract protected the end organs by restoring the anti-oxidants enzyme, significantly increasing super oxide dismutase level(SOD) and decreasing catalase(CAT) and TBARS level in visceral organs. In conclusion, that EPE extracts showed anti-diabetic and anti-oxidant potential against streptozotocin-induced diabetes. | Salanee Kandandapani Ashok K.Balaraman Haja N.Ahamed | 2015 | Chinese Journal of Natural Medicines2015，13，9： | 18 |
| 12 | 肝移植术后晚期合并多器官功能衰竭主要死因分析显示文摘目的 探讨肝移植术后晚期导致患者死亡的主要原因 ,提出预防的方法。方法 回顾性分析1981年 2月— 1998年 4月在美国匹斯堡大学进行的生存期大于 1年的 2 94 0例肝移植长期随访结果 ,分析其主要死因与相关因素。结果 1981— 1991年 10年肝移植术后病死率呈逐年降低趋势 ,从 2 0 .4 %降到 1.9% ;术后晚期 (存活期 >1年 )死亡者 817例 ,主要死因依次为恶性肿瘤 (复发 +新生 ,2 0 .7% )、心血管并发症( 11.4 % )、各种感染 ( 11.3% )和呼吸系统并发症 ( 9.4 % )。随着免疫抑制剂使用情况的变化 ,1981— 1986年为环胞素 / Cy A,1986— 1990年为 OKT3/ Viaspan,1991— 1998年为 Tarolim us/ FK5 0 6 ,各期 1、5、10年病死率呈逐年下降趋势。术后 1、5、10、15和 18年病死率以 3~ 18岁年龄为低 ,19~ 6 0岁年龄组 10、15、18年病死率最高。病死率最高的肝移植指征为恶性肿瘤和暴发性肝功能衰竭 ,酒精性肝硬化术后随时间延长病死率逐年增加 ,13年最高 (达 76 .0 % )。结论 肝移植术后期主要死因为新生恶性肿瘤、心血管并发症、各种感染和呼吸系统并发症 ; | 潘澄 Ashok Jain John J.Fung | 2004 | 中国危重病急救医学2004，16，9： | 16 |
| 13 | Head mass in chronic pancreatitis: Inflammatory or malignant显示文摘Chronic pancreatitis increases the risk of developing pancreatic cancer. This often presents as a mass lesion in the head of pancreas. Mass lesion in the head of pancreas can also occur secondary to an inflammatory lesion. Recognising this is crucial to avoid unnecessary surgery. This is sometimes difficult as there is an overlap in clinical presentation and conventional computed tomography(CT) abdomen findings in inflammatory andmalignant mass. Advances in imaging technologies like endoscopic ultrasound in conjunction with techniques like fine needle aspiration, contrast enhancement and elastography as well as multidetector row CT, magnetic resonance imaging and positron emission tomography scanning have been shown to help in distinguishing inflammatory and malignant mass. Research is ongoing to develop molecular techniques to help characterise focal pancreatic mass lesions. This paper reviews the current status of imaging and molecular techniques in differentiating a benign mass lesion in chronic pancreatitis and from malignancy. | Amit K Dutta Ashok Chacko | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，3： | 16 |
| 14 | Antioxidant and antipyretic properties of methanolic extract of Amaranthus spinosus leaves显示文摘Objective:Methanolic extract of Amaranthus spinosus(A.spinosus) leaves was screened for antioxidant and antipyretic activities.Methods:Antioxidant activity was measured by l,l-diphenyl-2-picryl-hydrazile(DPPH) free radical scavenging,superoxide anion radical scavenging,hydroxyl free radical scavenging,nitric oxide radical scavenging,2,2 -azinobis-3- ethylbenzothiazole-6-sulfonic acid(ABTS) radical scavenging assays and total phenolic content was also determined.Antipyretic activity of methanolic extract of A.spinosus was measured by yeast induced pyrexia method at concentration of 200 and 400 mg/kg using paracetamol as standard drug.Results:Methanolic extract of A.spinosus showed potent antioxidant activity.The IC50 value was(87.50±3.52)μg/mL,(98.80±1.40)μg/mL,(106.25±0.20)μg/mL,(88.70±0.62)μg/mL and(147.50±2.61)μg/mL for DPPH,superoxide,hydroxyl,nitric oxide and ABTS radical scavenging activities.Methanolic extract of A spinosus showed significant(P<0.01) antipyretic activity. | Bagepalli Srinivas Ashok Kumar Kuruba Lakshman Jayaveera KN Devangam Sheshadri Shekar Avalakondarayappa Arun Kumar Bachappa Manoj | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 15 |
| 15 | Obesity: modern man's fertility nemesis显示文摘肥胖流行成长了到有关最近的年里,不是仅仅在西方的世界上的比例,但是在也开发国家。在男富饶和肥沃的相应减少可以向肥胖在平行被解释,并且肥胖应该被看作男富饶的病原学。研究证明肥胖由减少精液质量贡献不孕,改变精子 proteomes,贡献可勃起的机能障碍,并且导致与肥胖有关的另外的物理问题。为在男不孕上解释肥胖的效果的机制包括睡觉呼吸暂停和增加的阴囊的温度包括反常繁殖荷尔蒙层次,与肥胖联系的脂肪质导出荷尔蒙和 adipokines 的一个增加的版本,和另外的物理问题。最近,为肥胖相关的不孕的基因因素和标记被发现了并且可以解释肥沃的肥胖、不肥沃的肥胖的人之间的差别。处理为与肥胖有关的不孕是可得到的不仅,而且作为为从肥胖产生的另外的 comorbidities 的一个处理。自然重量损失,以及 bariatric 外科是为肥胖的病人的选择并且在恢复富饶和正常神经质的侧面显示出有希望的结果。脂肪质导出荷尔蒙的治疗学的干预包括 aromatase 禁止者,外长的睾丸激素代替治疗和维护和规定,特别地 leptin,可能也能在肥胖的男性恢复富饶。因为在这个区域的研究的相对不知道和缺乏,控制了研究应该被承担,更多的焦点应该作为男不孕的 etiolgy 被给肥胖。 | Stephanie Cabler Ashok Agarwal Margot Flint Stefan S. Du Plessis | 2010 | Asian Journal of Andrology2010，12，4： | 14 |
| 16 | 再次肝移植——挽救肝移植失败受体生命唯一的手段(附774例报告)显示文摘目的 评估肝移植 ,尤其是再次肝移植的长期随访结果及影响结果的因素。方法 对1981年 2月至 1998年 4月期间进行的、存活时间大于 2年的 40 0 0例肝移植进行随访 ,其中再次肝移植 774例。根据首次肝移植的时间 ,分为A、B、C三期。结果 774例 (19 4% )接受第 2次肝移植 ,148例 (3 7% )接受第 3次肝移植 ,2 0例 (0 5 % )接受第 4次肝移植 ,5例 (0 13% )接受第 5次及 5次以上肝移植。第 1次再移植原因主要为移植肝原发性无功能、肝动脉栓塞和排斥反应。C期再次肝移植率 (13 4% )明显低于A期 (33 4% )和B期 (2 3 7% ) ,P =0 0 0 1。结论 掌握适当的再移植指征、再次手术时机、受体的选择和手术技巧 ,再次肝移植的长期生存率明显改善。 | 朱岳 江春平 John J. Fung Ashok Jain | 2002 | 中华肝胆外科杂志2002，8，11： | 14 |
| 17 | Varicocele and male infertility: current concepts and Future perspectives显示文摘Andrology 的亚洲杂志的这期特刊充分被奉献给精索静脉曲张的题目的区域,它是泌尿学, Andrology,和繁殖的药的地里的最争论的期之一。作为一个临床的实体认出了为在一个世纪,从拉丁文的精索静脉曲张:静脉曲张(扩大静脉) 并且从希腊语:kele (肿瘤) 仍然在男富饶和 gonadal 功能上在可争辩的否定效果上在科学家和临床医生之中得到激烈的争论并且自从它的第一在 18 th 世纪。 | Ashok Agarwal Sandro C Esteves | 2016 | Asian Journal of Andrology2016，18，2： | 13 |
| 18 | Lycopene and male infertility显示文摘反应的氧种类(ROS ) 的过多的数量引起氧化应力的一个状态,它导致精子膜类脂化合物 peroxidation, DNA 损坏和 apoptosis,导致减少的精子生存能力和活动性。ROS 的提高的层次是自发的男因素不孕的一个主要原因,它是今天的一个逐渐地普通的问题。Lycopene,所有类胡萝卜素的大多数有势力汗衫氧 quencher,因为它的抗氧化剂性质,是为男不孕的一种可能的处理选择。由反应与并且抵销自由激进分子, lycopene 能减少氧化应力的发生并且这样,减少将不那样被施加在精子身上的损坏。lycopene 可以在睾丸经由 nonoxidative 机制有另外的有益的效果,这被要求,例如差距连接通讯,基因表示的调整,房间周期和 immunoenhancement 的规定。在人和动物上进行的各种各样的 lycopene 补充研究在减轻男 infertility— 显示出有希望的结果;当精子计数和生存能力,和一般免疫被增加时,类脂化合物 peroxidation 和 DNA 损坏被减少。这些参数的改进在氧化应力显示减小,并且这样精子对氧化损坏不太脆弱,它增加使肥沃的一个正常精子的机会卵。人的试用每天与 lycopene 的 4-8 mg 的补充在精子参数和怀孕率报导改进 3-12 月了。然而,进一步详细说明了,广泛的研究仍然被要求为男不孕作为一个处理决定剂量和 lycopene 的实用性。 | Damayanthi Durairajanayagam Ashok Agarwal Chloe Ong Pallavi Prashast | 2014 | Asian Journal of Andrology2014，16，3： | 13 |
| 19 | Effect of varicocele on semen characteristics according to the new 2010 World Health Organization criteria: a systematic review and meta-analysis显示文摘这研究在不肥沃的人在精液参数上调查了精索静脉曲张的效果基于新人的精液的考试的 2010 世界健康组织实验室手册。精液分析结果(体积,精子计数,活动性,和形态学) 是主要结果。收集数据的电子搜索用 Medline/PubMed 被进行, SJU 发现,并且 Google 学者数据库。我们寻找了从 2010 出版到 2015 年 8 月的文章,即,在出版以后 2010 用手。我们包括了仅仅报导成年的不肥沃的人的实际精液参数与临床的精索静脉曲张诊断了并且包含了没与精索静脉曲张被诊断的肥沃的人或 normozoospermic 人的一个控制组的那些研究。十研究在元分析被包括,包含 1232 个人。精索静脉曲张与减少的精子计数被联系(吝啬的差别:− 44.48 ×10 6 ml −1 ;95% CI:− 61.45, − 27.51 ×10 6 ml −1 ;P <0.001 ) ,活动性(吝啬的差别:− 26.67% ;95% CI:− 34.27, − 19.08;P <0.001 ) ,并且形态学(吝啬的差别:− 19.68% ;95% CI:− 29.28, − 10.07;P <0.001 ) 然而并非精液体积(吝啬的差别:− 0.23 ml;95% CI:− 0.64, 0.17 ) 。亚群分析显示效果的大小被控制子类型影响然而并非实验室手册编辑为精液评价使用了。我们断定那精索静脉曲张是否定地在精液参数上影响精液质量,而是观察分享的效果尺寸的一个重要风险因素不似乎被 WHO 实验室手册编辑影响。在 2010 仍然为精液分析利用了 1999 手册以后,出版的研究的给定的大多数,进一步的研究被要求充分理解临床的含意 2010 在精索静脉曲张和精液参数之间的协会上的实验室手册。 | Ashok Agarwal Reecha Sharma Avi Harle Sandro C Esteves | 2016 | Asian Journal of Andrology2016，18，2： | 13 |
| 20 | Computer vision-based limestone rock-type classification using probabilistic neural network显示文摘Proper quality planning of limestone raw materials is an essential job of maintaining desired feed in cement plant. Rock-type identification is an integrated part of quality planning for limestone mine. In this paper, a computer vision-based rock-type classification algorithm is proposed for fast and reliable identification without human intervention. A laboratory scale vision-based model was developed using probabilistic neural network(PNN) where color histogram features are used as input. The color image histogram-based features that include weighted mean, skewness and kurtosis features are extracted for all three color space red, green, and blue. A total nine features are used as input for the PNN classification model. The smoothing parameter for PNN model is selected judicially to develop an optimal or close to the optimum classification model. The developed PPN is validated using the test data set and results reveal that the proposed vision-based model can perform satisfactorily for classifying limestone rocktypes. Overall the error of mis-classification is below 6%. When compared with other three classification algorithms, it is observed that the proposed method performs substantially better than all three classification algorithms. | Ashok Kumar Patel Snehamoy Chatterjee | 2016 | Geoscience Frontiers2016，7，1： | 13 |
您所在的机构暂未开通此部分的功能，请联系管理员