|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | NEW TOXOPLASMA GONDII GENOTYPES ISOLATED FROM FREE-RANGE CHICKENS FROM THE FERNANDO DE NORONHA, BRAZIL: UNEXPECTED FINDINGS显示文摘 | Dubey J P Rajendran C Costa D G C Ferreira L R Kwok O C H Qu D Su C Marvulo M F V Alves L C Mota R A Silva J C R | 2010 | The Journal of Parasitology2010，，4： | 2 |
| 2 | Microstructure and flowbehavior of liquid water- gelatine-locust bean gum systems 显示文摘 | M M Alves C Gamier J Lefebvre | 2001 | Food Hydrocolloids2001，15，： | 1 |
| 3 | Effects of a Saccharomyces cerevisiae yeast on ruminal fermentation and fibre degradation of maize silages in cows显示文摘 | Guedes C M Gon alves D Rodrigues M A M | 2008 | Anim Feed Sci Tech2008，145，1： | 1 |
| 4 | 'Effect of tillage on fractal indices describing soil surface microrelief of a Brazilian Alfisol显示文摘 | Vi~lal'V~izquez E /Vliranda J G V Alves M C | 2006 | Geoderma2006，134，3： | 1 |
| 5 | Evaluation of pharyngeal airway space amongst different skeletal patterns显示文摘 | Alves M Jr Franzotti ES Baratieri C | 2012 | Int J Oral Max- illofac Surg2012，41，7： | 1 |
| 6 | RBS lattice site location and damage recovery studies in GaN 显示文摘 | Alves E DaSilva M F Soares J C | 1999 | MRS Internet J Nitride Semiconductor Res1999，4，1： | 1 |
| 7 | On the existence and con- centration behaviour of ground state solutions for a class of problems with critical growth 显示文摘 | Alves C O Souto M A S | 2002 | Comm Pure Appl Anal2002，3，： | 1 |
| 8 | On systems of elliptic equations involving subcritical or critical Sobolev exponents显示文摘 | Alves C O Filho D C de M Souto M A S | 2000 | Nonlinear Analysis2000，42，： | 1 |
| 9 | Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy显示文摘AIM:To evaluate the potential use of colonoscopy and endoluminal ultrasonic biomicroscopy(eUBM)to track the progression of mouse colonic lesions.METHODS:Ten mice were treated with a single azoxy-methane intraperitoneal injection(week 1)followed by seven days of a dextran sulfate sodium treatment in their drinking water(week 2)to induce inflammationassociated colon tumors.eUBM was performed simultaneously with colonoscopy at weeks 13,17-20 and21.A 3.6-F diameter 40 MHz mini-probe catheter was used for eUBM imaging.The ultrasound mini-probe catheter was inserted into the accessory channel of a pediatric flexible bronchofiberscope,allowing simultaneous acquisition of colonoscopic and eUBM images.During image acquisition,the mice were anesthetized with isoflurane and kept in a supine position over a stainless steel heated surgical waterbed at 37℃.Both eUBM and colonoscopic images were captured and stored when a lesion was detected by colonoscopy or when the eUBM image revealed a modified colon wall anatomy.During the procedure,the colon was irrigated with water that was injected through a flush port on the mini-probe catheter and that acted as the ultrasound coupling medium between the transducer and the colon wall.Once the acquisition of the last eUBM/colonoscopy section for each animal was completed,the colons were fixed,paraffin-embedded,and stained with hematoxylin and eosin.Colon images acquired at the first time-point for each mouse were compared with subsequent eUBM/colonoscopic images of the same sites obtained in the following acquisitions to evaluate lesion progression.RESULTS:All 10 mice had eUBM and colonoscopic images acquired at week 13(the first time-point).Two animals died immediately after the first imaging acquisition and,consequently,only 8 mice were subjected to the second eUBM/colonoscopy imaging acquisition(at the second time-point).Due to the advanced stage of colonic tumorigenesis,5 animals died after the second time-point image acquisition,and thus,only three were subjected to the third eUBM/colonoscopy imaging acquisition(the third time-point).eUBM was able to detect the four layers in healthy segments of colon:the mucosa(the first hyperechoic layer moving away from the mini-probe axis),followed by the muscularis mucosae(hypoechoic),the submucosa(the second hyperechoic layer)and the muscularis externa(the second hypoechoic layer).Hypoechoic regions between the mucosa and the muscularis externa layers represented lymphoid infiltrates,as confirmed by the corresponding histological images.Pedunculated tumors were represented by hyperechoic masses in the mucosa layer.Among the lesions that decreased in size between the first and third time-points,one of the lesions changed from a mucosal hyperplasia with ulceration at the top to a mucosal hyperplasia with lymphoid infiltrate and,finally,to small signs of mucosal hyperplasia and lymphoid infiltrate.In this case,while lesion regression and modification were observable in the eUBM images,colonoscopy was only able to detect the lesion at the first and second time-points,without the capacity to demonstrate the presence of lymphoid infiltrate.Regarding the lesions that increased in size,one of them started as a small elevation in the mucosa layer and progressed to a pedunculated tumor.In this case,while eUBM imaging revealed the lesion at the first time-point,colonoscopy was only able to detect it at the second time-point.All colonic lesions(tumors,lymphoid infiltrate and mucosal thickening)were identified by eUBM,while colonoscopy identified just76%of them.Colonoscopy identified all of the colonic tumors but failed to diagnose lymphoid infiltrates and increased mucosal thickness and failed to differentiate lymphoid infiltrates from small adenomas.During the observation period,most of the lesions(approximately67%)increased in size,approximately 14%remained unchanged,and 19%regressed.CONCLUSION:Combining eUBM with colonoscopy improves the diagnosis and the follow-up of mouse colonic lesions,adding transmural assessment of the bowel wall. | Rossana C Soletti Kelly Z Alves Marcelo AP de Britto Dyanna G de Matos Mnica Soldan Helena L Borges Joo C Machado | 2013 | World Journal of Gastroenterology2013，19，44： | 1 |
| 10 | Parallel strategies for the local biological sequence alignment in a cluster of workstations显示文摘 | Boukerche A Alves de Melo A C M Ayala-Rincon M | 2007 | Journal of Parallel and Distributed Computing2007，67，2： | 1 |
| 11 | New multi-phase sys- tems based on tin compounds active for vegetable oil transesteri- fication reaction显示文摘 | ABREU F R ALVES M B MACEDO C C | 2005 | Journal of Molecular A Chemical2005，227，： | 1 |
| 12 | RAS strategy for IBM S/390 G5 and G6 显示文摘 | M Mueller L C Alves W Fischer | 1999 | IBM Journal of Research and Development1999，43，56： | 1 |
| 13 | Assessment of mini-implant displacement using cone beam com- puted tomography显示文摘 | Alves M Jr Baratieri C Nojima LI | 2011 | Clin Oral Implants Res2011，22，10： | 1 |
| 14 | End-to-end joining of tubes by plastic instability 显示文摘 | Alves L M Silva C M A Martins P A F | 2014 | Journal of Materials Processing Technology2014，214，9： | 1 |
| 15 | Quantitative study of caspase-3 activity in semen and after swim-up preparation in relation to sperm quality显示文摘 | Almeida C Cardoso MF Sousa M Viana P Gon(c)alves A Silva J | 2005 | Hum Reprod2005，20，5： | 1 |
| 16 | Isolation and initial characterization of a bacterial consortium able to mineralize fluorobenzene显示文摘 | Carvalho M F Alves C C T Ferreira M I M | 2002 | Applied and Environmental Microbiology2002，68，1： | 1 |
| 17 | Organic particulate emissions from field burning of garden and agriculture residues显示文摘 | Goncalves C Evtyugina M Alves C | 2011 | Atmospheric Research2011，101，3： | 1 |
| 18 | Lean production as promoter of thinkers to achieve companies' agility 显示文摘 | Alves A C Dinis-Carvalho J Sousa R M | 2012 | The Learning Organiza- tion2012，19，3： | 1 |
| 19 | Changes in volatile com- position of Madeira wines during their oxidative ageing显示文摘 | Ci MARA J S ALVES M A MARQUES J C | 2006 | Anal Chim Acta2006，563，1： | 1 |
| 20 | Organic particulate emissions from field burning of garden and agriculture residues 显示文摘 | Goncalves C Evtyugina M Alves C | 2011 | Atmospheric Research2011，101，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员