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| 1 | The Association of Maternal Body Composition and Dietary Intake with the Risk of Gestational Diabetes Mellitus during the Second Trimester in a Cohort of Chinese Pregnant Women显示文摘Objective To investigate the association of maternal body composition and dietary intake with the risk of gestational diabetes mellitus(GDM). Methods A total 154 GDM subjects and 981 controls were enrolled in a prospective cohort study in 11 hospitals from May 20, 2012 to December 31, 2013. Bioelectrical impedance analysis and dietary surveys were used to determine body composition and to evaluate the intake of nutrients in subjects at 21-24 weeks' gestation(WG). Logistic regression analysis was applied to explore the relationships of maternal body composition and dietary intake with the risk of GDM morbidity. Results Age, pre-pregnant body weight(BW), and body mass index(BMI) were associated with increased risk of GDM. Fat mass(FM), fat mass percentage(FMP), extracellular water(ECW), BMI, BW, energy, protein, fat, and carbohydrates at 21-24 WG were associated with an increased risk of GDM. In contrast, fat free mass(FFM), muscular mass(MM), and intracellular water(ICW) were associated with a decreased risk of GDM. Conclusion Maternal body composition and dietary intake during the second trimester of pregnancy were associated with the risk of GDM morbidity. | Xu Qing Gao Zhi Ying Li Li Ming Wang Lu Zhang Qian Teng Yue Zhao Xia Ge Sheng Jing Hong Jiang Yang Yong Tao Liu Xiao Jun Lyu Chun Jian Mao Lun Yu Xiao Ming Liu Ying Hua Kong Ai Jing Yang Xue Yan Liu Zhao Zhang Yong Wang Jin Zhang Xin Sheng Xue Chang Yong Lu Yan Ping | 2016 | Biomedical and Environmental Sciences2016，29，1： | 29 |
| 2 | Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185^(c-erbB-2)显示文摘The c-erbB-2 proto-oncogene encodes a 185kDa protein p185, which belongs to epidermal growth factorreceptor family. Amplification of this gene has been shown to correlate with poor clinical prognosis forcertain cancer patients. The monoclonal antibody A21 which directed against p185 specifically inhibitsproliferation of tumor cells overexpressing p185, hence allows it to be a candidate for targeted therapy. Inorder to overcome several drawbacks of murine MAb, we cloned its VH and VL genes and constructed thesingle-chain Fv (scFv) through a peptide linker. The recombinant scFvA21 was expressed in Escherichiacoli and purified by the affinity column. Subsequently it was characterized by ELISA, Western blot, cellimmunohistochemistry and FACS. All these assays showed the binding activity to extracellular domain(ECD) of p185. Based on those properties of scFvA21, we further constructed the scFv-Fc fusion moleculewith a homodimer form and the recombinant product was expressed in mammalian cells. In a series ofsubsequent analysis this fusion protein showed identical antigen binding site and activity with the parentantibody. These anti-p185 engineered antibodies have promised to be further modified as a tumor targetingdrugs, with a view of application in the diagnosis and treatment of human breast cancer. | LIAN SHENG CHENG, AI PING LIU, JIA HONG YANG, YAN QIU DONG, LIANG WEI LI, JING WANG, CHAO CHEN WANG, JING LIUSchool of Life Science, University of Science and Technology of China, Hefei 230027, China | 2003 | Cell Research2003，13，1： | 24 |
| 3 | Heavy metal concentrations of agricultural soils and vegetables from Dongguan, Guangdong显示文摘118 农业土壤和 43 件蔬菜样品的一个总数从 Dongguan 城市被收集,广东,中国。空间分发,来源,累积特征和在农业土壤和蔬菜的重金属的潜在的风险被三条不同途径在细节描绘,包括在土壤和蔬菜的八个金属元素的全部的内容,在在学习的土壤的重金属的 GIS 地图和 multivariate 分析。结果证明在农业土壤有象 Cu , Zn , Ni , Pb , Cd 和 Hg 那样的重金属的更高的累积,并且 Pb 的内容( 65.38 mg kg ? 2 )并且 Hg ( 0.24 mg kg ? 2 )分别地是在广东省的土壤的相应重金属的背景内容的 1.82 和 2.82 次。有在附近的 3.4% Cu, 5.9% Ni, 1.7% Cd 和 28% Hg 在所有从有的所有调查地点收集了土壤样品溢出为为土壤标准的中国环境质量的重金属的内容(GB15618-1995,等级 II ) 。在土壤的多金属的污染特征被 Hg 主要反映。到在土壤的八个金属元素有不同来源, Cu, Zn, Ni, Cr 并且这是主要源于父母材料,并且 Pb, Hg 和 Cd 被人为的活动影响。空间分发表演 Cu, Zn, Ni, Cr, Pb 并且农业土壤的 Hg 内容在西方高并且在东方,和 Cd 内容低在西北高,东南并且在在 Dongguan 的西南低。Ni 的蔬菜样品的比率, Pb 并且作为比最大值高的集中,在食物(GB2762-2005 ) 的沾染物的层次分别地是 4.7% , 16.3% 和 48.8% 。在蔬菜的重金属的简历集中因素(BCF ) 的顺序是 Cd > Zn > Cu > 作为 > Ni > Hg > Cr > Pb。在 Dongguan 城市里从农业土壤和蔬菜为食物安全和人健康集中于重金属的潜在的风险是必要的,广东省。 | CAI Limei HUANG Lanchun ZHOU Yongzhang XU Zhencheng PENG Xiaochun YAO Ling'ai ZHOU Yang PENG Ping'an | 2010 | Journal of Geographical Sciences2010，20，1： | 23 |
| 4 | Pharmacokinetics of traditional Chinese syndrome and recipe:a hypothesis and its verification(Ⅰ)显示文摘AIM To propose a hypothesis defining theabsorption,distribution,metabolism andelimination of traditional Chinese recipe(TCR)-component in blood of healthy subjects andpatients,and estimate its correctness.METHODS The pharmacokinetics(PK)of samedose of drug was studied in the animal model oftraditional Chinese syndrome(S)and healthyanimals.The classification,terminology,concept and significance of the hypothesis wereset forth with evidence provided in the presentstudy.The hypotheses consisted of traditionalChinese syndrome PK(S-PK)and traditionalChinese recipe PK(R-PK).Firstly,the observedtetramethylpyrazine(TMP)PK in healthy,chronically reserpinized rats(rat model ofspleen deficiency syndrome,RMSDS)andRMSDS treated with Sijunzi decoction(SJZD)forconfirmation were used to verify S-PK; secondly,the ferulic acid(FA)PK in healthy andhigh molecular weight dextran(HMWD)-inducedrabbit model with blood stasis syndrome(RDBSS)was also used to verify S-PK;andlastly,TMP PK parameters in serum of healthyrats after orally taken Ligusticum wallichii(LW),LW and Salvia miltiorrhiza(LW&SM)decoctions were compared to verify R-PK.RESULTS The apparent first-order absorption[Ka,(13.61±2.56)h-1,area under the blooddrug concentration-time curve[AUC,(24.88±9.76)μg.h-1mL-1],maximum drug concentration[Cmax,(4.82±1.23)μg·mL-1]of serum TMP inRMSDS were increased markedly(P<0.05)compared with those[Ka=(5.41±1.91)h-1,AUC=(5.20±2.57)μg·h-1·mL-1,Cmax=(2.33±1.77)μg·mL-1]of healthy rats(HR).Theapparent first-order rate constant for α and βdistribution phase[α=(0.38±0.09)h-1,β=(0.06±0.03)h-1,the apparent first-orderintercompartmental transfer rate constants[K10=(0.24±0.07)h-1,K12=(0.11±0.02)h-1,K21=(0.11±0.02)h-1]of serum TMP in RMSDS weredecreased significantly(P<0.01)comparedwith those[K10=(0.88±0.20)h-1,K12=(1.45±0.47)h-1,K21=(0.72±0.22)h-1]of HR.However,no apparent differences occurredbetween HR and RMSDS treated with SJZD.Theserum FA concentration and its AUC[(5.6690±2.3541)μg·h-1·mL-1] in RMBSS were also higherthan those[AUC=(2.7566±0.8232)μg·h-1·mL-1]of healthy rabbits(P<0.05).The Ka(11.51±2.82)h-1,AUC(0.84±0.17)μg·h-1·mL-1of LW & SM-derived TMP in serum weremuch lower(P<0.05)than those[Ka=(19.58±4.14)h-1,AUC=(1.27±0.26)μg·h-1·mL-1]ofLW-derived TMP in serum after oral decoctions.CONCLUSION The SDS and blood stasissyndrome state could affect significantly thepharmacokinetic parameters of drugs and theabnormal SDS pharmacokinetic parameters couldbe normalized by SJZD.The combination ofChinese medicine in TCR could reciprocallyaffect the pharmacokinetic parameters of othercomponents absorbed into the systemiccirculation.These results support the S-and R-PK hypothesis. | Xi Huang Ping Ren Ai Dong Wen Li Li Wang Li Zhang Feng Gao Laboratory of Clinical Pharmacology of Chinese Medicine,Xijing Hospital,The Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China Department of Pharmacy,Xijing Hospital,The Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China Department of Physiology,The Fourth Military Medical University,Xi’an 710032,Shaanxi Province,China | 2000 | World Journal of Gastroenterology2000，6，3： | 16 |
| 5 | Genotypic Characterization of Methicillin-resistant Staphylococcus aureus Isolated from Pigs and Retail Foods in China显示文摘Objective To investigate the genotypic diversity of Methicillin-resistant Staphylococcus aureus(MRSA) isolated from pigs and retail foods from different geographical areas in China and further to study the routes and rates of transmission of this pathogen from animals to food. Methods Seventy-one MRSA isolates were obtained from pigs and retail foods and then characterized by multi-locus sequencing typing(MLST), spa typing, multiple-locus variable number of tandem repeat analysis(MLVA), pulsed-field gel electrophoresis(PFGE), and antimicrobial susceptibility testing. Results All isolated MRSA exhibited multi-drug resistance(MDR). Greater diversity was found in food-associated MRSA(7 STs, 8 spa types, and 10 MLVA patterns) compared to pig-associated MRSA(3 STs, 1 spa type, and 6 MLVA patterns). PFGE patterns were more diverse for pig-associated MRSA than those of food-associated isolates(40 vs. 11 pulse types). Among the pig-associated isolates, CC9-ST9-t899-MC2236 was the most prevalent clone(96.4%), and CC9-ST9-t437-MC621(20.0%) was the predominant clone among the food-associated isolates. The CC9-ST9 isolates showed significantly higher antimicrobial resistance than other clones. Interestingly, CC398-ST398-t034 clone was identified from both pig-and food-associated isolates. Of note, some community-and hospital-associated MRSA strains(t030, t172, t1244, and t4549) were also identified as food-associated isolates. Conclusion CC9-ST9-t899-MC2236-MDR was the most predominant clone in pigs, but significant genetic diversity was observed in food-associated MRSA. Our results demonstrate the great need for improved surveillance of MRSA in livestock and food and effective prevention strategies to limit MDR-MRSA infections in China. | WANG Wei LIU Feng ZULQARNAIN Baloch ZHANG Cun Shan MA Ke PENG Zi Xin YAN Shao Fei HU Yu Jie GAN Xin DONG Yin Ping BAI Yao LI Feng Qin YAN Xiao Mei MA Ai Guo XU Jin | 2017 | Biomedical and Environmental Sciences2017，30，8： | 13 |
| 6 | Methodology and Application for Health Risk Classification of Chemicals in Foods Based on Risk Matrix显示文摘The method has been developed to accurately identify the magnitude of health risks and provide scientific evidence for implementation of risk management in food safety.It combines two parameters including consequence and likelihood of adverse effects based on risk matrix.Score definitions and classification for the consequence and the likelihood of adverse effects are proposed.The risk score identifies the intersection of consequence and likelihood in risk matrix represents its health risk level with different colors:‘low',‘medium',‘high'.Its use in an actual case is shown. | ZHOU Ping Ping LIU Zhao Ping ZHANG Lei LIU Ai Dong SONG Yan YONG Ling LI Ning | 2014 | Biomedical and Environmental Sciences2014，27，11： | 11 |
| 7 | Simple preparation and catalytic properties of ZnO for ozonation degradation of phenol in water显示文摘ZnO 粒子大约 200 nm 通过一个灵巧的热水的方法被准备。与单个 ozonation 相比,酚的降级效率增加了大约 23.7% ,中介的降级效率在 298 K 面对 ZnO 改善了大约四次。另外,催化剂在 ozonation 过程有好稳定性。温度的影响被调查,更好的催化作用效率能在更低的温度被获得,这被发现。 | Yu Ming Dong Guang Li Wang Ping Ping Jiang Ai Min Zhang Lin Yue Xiao Ming Zhang | 2011 | Chinese Chemical Letters2011，22，2： | 9 |
| 8 | Relationship between microorganisms in coronary atheromatous plaques and periodontal pathogenic bacteria显示文摘 | ZHANG Yuan-ming ZHONG Liang-jun LIANG Ping LIU Hua MU La-ti AI Si-ka-er | 2008 | Chinese Medical Journal2008，，16： | 9 |
| 9 | Survey of coverage,strategy and cost of hepatitis B vaccination in rural and urban areas of China显示文摘INTRODUCTIONSomestudiesdemonstratedthatHBsAgandantiHBcpositiveratesoftheimmunizedpopulationsafterhepatitisB(HB)vaccination... | ZENG Xian Jia 1, YANG Gong Huan 2, LIAO Su Su 1, CHEN Ai Ping 2, TAN Jian 2, HUANG Zheng Jing 2 and LI Hui 1 | 1999 | World Journal of Gastroenterology1999，5，4： | 8 |
| 10 | Regulation of Survivin and CDK4 by Epstein-Barr virus encoded latent mem-brane protein 1 in nasopharyngeal carcinoma cell lines显示文摘Latent membrane protein 1 (LMP1), an important protein encoded by Epstein Barr virus (EBV), has been implied to link with the pathogenesis of nasopharyngeal carcinoma (NPC). Its dual effects of increasing cell proliferation and inhibiting cell apoptosis have been confirmed. In this study, we showed that the expression of Survivin and CDK4 protein in CNE-LMP1, a LMP1 positive NPC epithelial cell line, is higher than in LMP1 negative NPC epithelial cell line- CNE1, and the expression is LMP1 dosage-dependent. Although it was reported that Survivin specifically expressed in cell cycle G2/M phase, our studies suggested that LMP1 could promote the expression of Survivin in G0/G1, S and G2/ M phase. It also showed that Survivin and CDK4 could be accumulated more in the nuclei triggered by LMP1. More interestingly, Survivin and CDK4 could form a protein complex in the nuclei of CNE-LMP1 rather than in that of CNE1, which demonstrated that the interaction between these two proteins could be promoted by LMP1. These results strongly suggested that the role of LMP1 in the regulation of Survivin and CDK4 may also shed some light on the mechanism research of LMP1 in NPC. | Mi Dan AI Li Li LI Xiao Rong ZHAO Yong WU Jian Ping GONG Ya CAO | 2005 | Cell Research2005，15，10： | 8 |
| 11 | Design,Synthesis and in vitro Evaluation of a New Class of Novel Cyclooxygenase-2 Inhibitors:3,4-diaryl-3-pyrrolin-2-ones显示文摘design, synthesis and in vivo evaluation of a new class of COX-2 inhibitors 3, 4-diaryl-3-pyrrolin-2-ones are reported. | Ai Ping BAI, Zong Ru GUO*, Wen Hui HU, Fang SHEN, Gui Fang CHENG Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050 | 2001 | Chinese Chemical Letters2001，12，9： | 7 |
| 12 | The preoperative serum cystatin-C as an independent prognostic factor for survival in upper tract urothelial carcinoma显示文摘Cystatin-C(Cys-C)has been reported as a valuable prognostic biomarker in various malignancies.However,its effect on upper tract urothelial carci noma(UTUC)patie nts has not bee n investigated before.Thus,to explore the impact of Cys-C on survival outcomes in patients undergoing radical nephroureterectomy(RNU),a total of 538 patients with UTUC who underwent RNU between 2005 and 2014 in our center(West China Hospital,Chengdu,China)were included in this study.Kaplan-Meier method and Cox regressi on an a lyses were performed to assess the relationship betwee n Cys-C and survival outcomes using SPSS versi on 22.0.The cutoff value of Cys-C was set as 1.4 mg I1 using the receiver operating characteristic(ROC)curves and Youden index.The mean age of patients included was 66.1±11.1 years,and the media n follow-up durati on was 38(interquartile ran ge:19-56)mon ths.Overall,162(30.1%)patients had elevated Cys-C,and they were much older and had worse renal function than those with Cys-C<1.4 mg I^-1(both P<0.001).Meanwhile,Kaplan-Meier analysis revealed that the group with elevated Cys-C had worse cancer-specific survival(CSS,P=0.001),disease recurrence-free survival(RFS,P=0.003),and overall survival(OS,P<0.001).Multivariable Cox analysis suggested that the elevated Cys-C was identified as an independent prognostic predictor of CSS(hazard ratio[HR]:1.997,95%confidential interval[CI]:1.331-2.996),RFS(HR:1.429,95%CI:1.009-2.023),and OS(HR:1.989,95%CI:1.366-2.896).In conclusion,our result revealed that the elevated preoperative serum Cys-C was significantly associated with worse outcomes in UTUC patients undergoing RNU. | Ping Tan Ming Shi Jie Chen Hang Xu Nan Xie Huan Xu Yong Jiang Jian-Zhong Ai Liang-Ren Liu Lu Yang Qiang Wei | 2019 | Asian Journal of Andrology2019，21，2： | 7 |
| 13 | Epidermal growth factor receptor mutation analysis in cytological specimens and responsiveness to gefitinib in advanced non-small cell lung cancer patients显示文摘Background: Epidermal growth factor receptor(EGFR) mutation is the key predictor of EGFR tyrosine kinase inhibitors(TKIs) efficacy in non-small cell lung cancer(NSCLC). We conducted this study to verify the feasibility of EGFR mutation analysis in cytological specimens and investigate the responsiveness to gefitinib treatment in patients carrying EGFR mutations.Methods: A total of 210 cytological specimens were collected for EGFR mutation detection by both direct sequencing and amplification refractory mutation system(ARMS). We analyzed EGFR mutation status by both methods and evaluated the responsiveness to gefitinib treatment in patients harboring EGFR mutations by overall response rate(ORR), disease control rate(DCR) and progression free survival(PFS).Results: Of all patients, EGFR mutation rate was 28.6%(60/210) by direct sequencing and 45.2%(95/210) by ARMS(P<0.001) respectively. Among the EGFR wild type patients tested by direct sequencing, 26.7% of them were positive by ARMS. For the 72 EGFR mutation positive patients treated with gefitinib, the ORR, DCR and median PFS were 69.4%, 90.2% and 9.3 months respectively. The patients whose EGFR mutation status was negative by direct sequencing but positive by ARMS had lower ORR(48.0% vs. 80.9%, P=0.004) and shorter median PFS(7.4 vs. 10.5 months, P=0.009) as compared with that of EGFR mutation positive patients by both detection methods. Conclusions: Our study verified the feasibility of EGFR analysis in cytological specimens in advanced NSCLC. ARMS is more sensitive than direct sequencing in EGFR mutation detection. EGFR Mutation status tested on cytological samples is applicable for predicting the response to gefitinib. Abundance of EGFR mutations might have an influence on TKIs efficacy. | Lin Li Zijin Zhang Zhixin Bie Zheng Wang Ping Zhang Xin Nie Yuanming Li Hui Wang Bin Ai Gang Cheng | 2015 | Chinese Journal of Cancer Research2015，27，3： | 5 |
| 14 | Estimating the Health and Economic Outcomes of the Prevention of Mother-to-child Transmission of HIV Using a Decision Tree Model显示文摘In 2016, there were 17.8 million (15.4-20.3 million) women living with HIV/AIDS across the world and the prevalence of reproductive desire among this group was 26%-49%[1]. If pregnant women living with HIV/AIDS are left untreated, the rates of HIV transmission from mother-to-child would range from 14% to 48%, depending on the presence and duration of breastfeeding[2]. | QU Shui Ling WANG Ai Ling PAN Xiao Ping WANG Qian DOU Li Xia ZHANG Tong | 2019 | Biomedical and Environmental Sciences2019，32，1： | 4 |
| 15 | Cytotoxic triterpenoid saponins from Ardisia pusilla显示文摘新 triterpenoid saponin, 3-O-{ β -d-xylopyranosyl-(1 →2 )-β-d-glucopyranosyl-(1 →4 )-[β-d-glucopyranosyl-(1 →2 )]-α-l-arabinopyranosyl}-3β,16α,28α-trihydroxy-13β,28-epoxy-oleanan-30-al (ardipusilloside III, 1 ) 和二已知的 saponins, ardisiacrispins A (2 ) 和 B (3 ) ,从 Ardisia pusilla A 的整个植物被孤立。DC。他们的结构被阐明由广泛光谱分析和化学证据。对人的 glioblastoma U251MG 房间的 Saponins 1 和 3 展出重要 cytotoxicity。 | Hai Feng Tang Hou Wen Lin Xiao Li Chen Guang Cheng Yue Ping Zhao Ai Dong Wen | 2009 | Chinese Chemical Letters2009，20，2： | 4 |
| 16 | Synthesis,spectroscopic and electrochemical property of an unsymmetrical porphyrin and its Zn compound显示文摘在这篇文章,新 5-(p-maleicaminophenyl )-10,15,20-triphenylporphyrin (H2P ) 和相对的锌化合物(ZnP ) 借助于元素的分析,紫外鈥搗i s,红外, MS 和 1H NMR 光谱学被综合并且描绘。而且,我们调查了这些混合物的荧光光谱学。混合物的氧化和减小性质被周期的 voltammetry 学习,氧化鈥搑e duction 潜力被获得。 | Chang Fu Zhuang Yu Jing Zhang Ai Qing Xia Wen Hui Lian Yun Fang Wang Ping Zhang Tong Shun Shi | 2010 | Chinese Chemical Letters2010，21，7： | 3 |
| 17 | Optimal Waist Circumference Cut-off values for Identifying Metabolic Risk Factors in Middle-aged and Elderly Subjects in Shandong Province of China显示文摘Objective To study the optimal waist circumference(WC) cut-off values for identifying metabolic risk factors in middle-aged and elderly subjects in Shandong Province of China. Methods A total of 2 873 men and 5 559 women were included in this cross-sectional study. Metabolic syndrome(MetS) was diagnosed according to the definition of Chinese Diabetes Society in 2004. The relation between WC and MetS was analyzed by multivariate logistic regression analysis. The optimal WC cut-off values were identified using the area under the ROC curve and the different diagnostic criteria for central obesity were compared. Results The WC was the risk factor for MetS independent of BMI, blood glucose, blood lipid, and blood pressure. The optimal WC cut-off value was 83.8 cm and 91.1 cm for identifying MetS in women and men, respectively. Compared with 80 cm and 85 cm for women and men, 85 cm and 90 cm had a higher Youden index for identifying all metabolic risk factors and MetS in women and men. Conclusion The appropriate WC cut-off value is 85 cm and 90 cm for identifying central obesity and MetS in women and men in Shandong Province of China. | HOU Xin Guo WANG Chuan MA Ze Qiang YANG Wei Fang WANG Ji Xiang LI Cheng Qiao WANG Yu Lian LIU Shu Min Hu Xiu Ping ZHANG Xiu Ping JIANG Mei WANG Wei Qing NING Guang ZHENG Hui Zhen MA Ai Xia SUN Yu SONG Jun LIN Peng LIANG Kai LIU Fu Qiang LI Wen Juan XIAO Juan GONG Lei WANG Mei Jian LIU Ji Dong YAN Fei YANG Jun Peng WANG Ling Shu TIAN Meng ZHAO Ru Xing JIANG Ling CHEN Li | 2014 | Biomedical and Environmental Sciences2014，27，5： | 3 |
| 18 | Chirality-assisted lateral momentum transfer for bidirectional enantioselective separation显示文摘Lateral optical forces induced by linearly polarized laser beams have been predicted to deflect dipolar particles with opposite chiralities toward opposite transversal directions.These“chirality-dependent”forces can offer new possibilities for passive all-optical enantioselective sorting of chiral particles,which is essential to the nanoscience and drug industries.However,previous chiral sorting experiments focused on large particles with diameters in the geometrical-optics regime.Here,we demonstrate,for the first time,the robust sorting of Mie(size~wavelength)chiral particles with different handedness at an air–water interface using optical lateral forces induced by a single linearly polarized laser beam.The nontrivial physical interactions underlying these chirality-dependent forces distinctly differ from those predicted for dipolar or geometrical-optics particles.The lateral forces emerge from a complex interplay between the light polarization,lateral momentum enhancement,and out-of-plane light refraction at the particle-water interface.The sign of the lateral force could be reversed by changing the particle size,incident angle,and polarization of the obliquely incident light. | Yuzhi Shi Tongtong Zhu Tianhang Zhang Alfredo Mazzulla Din Ping Tsai Weiqiang Ding Ai Qun Liu Gabriella Cipparrone Juan Jose Saenz Cheng-Wei Qiu | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 19 | Trans Fatty Acid Levels in Foods and Intakes among Population Aged 3 Years and above in Beijing and Guangzhou Cities,China显示文摘Objective To understand the dietary intake levels of trans fatty acids(TFA) in a Chinese population and establish a basis for health risk assessment of trans fatty acids. Methods The TFA contents data of 2613 food items and food consumption data of 10,533 people aged 3 years and above in two large cities in China were matched and a simple assessment method was used to estimate the distribution of dietary TFA intake. Results The mean content of TFA was highest in margarine(1.68±0.83 g/100g), followed by chocolate and candy(0.89±2.68 g/100g), edible vegetable oils(0.86±0.82 g/100g), milk(0.83±1.56 g/100g), and bakery foods(0.41±0.91 g/100g). TFA intake accounted for 0.34%, 0.30%, 0.32%, and 0.29% of the total energy intake in the 3-6, 7-12, 13-17, and ≥18 year age groups, respectively. Of the populations studied, 0.42% demonstrated TFA intakes(as percentage of energy intake) greater than 1%. The main sources of dietary TFA intake were edible vegetable oils, milk, mutton, and beef, and baked foods, which accounted for 49.8%, 16.56%, 12.21%, and 8.87%, respectively. Conclusion The current intake of TFA among people in two cities did not appear to be of major health concern regarding the threshold of TFA intake as the percentage of total energy recommended by the World Health Organization. Because most TFA were derived from industrially processed foods, the government should reinforce nutrition labeling and regulate food producers to further reduce TFA in food and to provide scientific instruction for consumers to make sound choices. | LIU Ai Dong LI Jian Wen LIU Zhao Ping ZHOU Ping Ping MAO Wei Feng LI Ning ZHANG Lei | 2015 | Biomedical and Environmental Sciences2015，28，7： | 3 |
| 20 | Enantioseparation of Aminoglutethimide by High-speed Countercurrent Chromatography Using Carboxymethly-β-cyclodextrin as Chiral Selector显示文摘Enantioseparation of aminoglutethimide was performed by high-speed counter-current chromatography with a two-phase system composed of ethyl acetate: methanol: water = 10: 1: 9. The lower phase contained 20 mmol/L of carboxymethly-β-cyclodextrin as chiral selector. The enantiomers were separated in 1.2 h and identified by chiral HPLC. This method was very efficient for the chiral preparative separation. | Ping AI Jia Chuan LIU Min ZI Zhi Hua DENG Zhi Hong YAN Li Ming YUAN | 2006 | Chinese Chemical Letters2006，17，6： | 3 |
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