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| 1 | 大兴安岭北部塔河堆晶辉长岩体的形成时代、地球化学特征及其成因显示文摘本文系统地报道了大兴安岭北部塔河辉长岩的主量元素、微量元素和锆石Hf同位素特征,重点讨论了塔河堆晶辉长岩体的岩石成因、原始岩浆的源区特征及其地质意义。研究结果表明,塔河堆晶辉长岩体SiO2含量从42.5%到47.4%,平均为45.2%,Al2O3为15.9-32.9%,平均为23.6%,大于17%,CaO为11.7-17.1%,TiO2<0.5%,P2O5<0.1%,富集LILE, 亏损HFSE,这些地球化学特征类似于活动大陆边缘或岛弧环境的辉长岩。激光ICP-MS锆石年龄测定结果显示,塔河辉长岩形成于333±8 Ma前。负的εHf(t)值(-2--5)表明其源区为富集型岩石圈地幔或下地壳。因此,本文推测,塔河堆晶辉长岩来自于地幔辉石岩的部分熔融,该源区的形成可能与俯冲背景下流体交代作用有关,从而表明在330 Ma左右,该区存在过板块的消减作用,可能与松嫩和兴安地块拼合有关。 | 周长勇 吴福元 葛文春 孙德有 Abdel RAHMAN A A 张吉衡 程瑞玉 | 2005 | 岩石学报2005，21，3： | 84 |
| 2 | Emplacement age of the Tahe granite and its constraints on the tectonic nature of the Ergun block in the northern part of the Da Hinggan Range显示文摘Large-scale granitic plutons are exposed in the Ergun block in the northern part of the Da Hinggan Range, but their emplacement age and petrogenesis remain un-known. Of these plutons, the Tahe pluton is composed mainly of porphyritic syenogranite and monzogranite, with minor hornblende alkali feldspar granite and gabbro, which have affinities to post-orogenic granitoids. Laser-ablation Induc-tively Coupled Plasma Mass-spectroscope (LA-ICP-MS) analysis shows that the major rock types of the Tahe pluton formed at 494-480 Ma ago, indicating its emplacement in the Early Paleozoic. It is concluded, therefore, that the colli-sion between the Ergun and the Xing’an blocks ended in Early Paleozoic. Considering the geochronological data of the plutons in the adjacent areas, the Early Paleozoic evolu-tionary history of the Ergun block is similar to the central Mongolia and the Tuvino blocks in Mongolia, and the Ergun block should be a part of the accretionary continental mar-gin in the southern Siberian Craton. | GE Wenchun WU Fuyuan ZHOU Changyong Abdel Rahman A. A. | 2005 | Chinese Science Bulletin2005，50，18： | 111 |
| 3 | 大兴安岭北段塔河辉长岩的岩石学特征及其构造意义显示文摘塔河辉长岩是大兴安岭北段塔河地区最具代表性的辉长岩体。该岩体主要由橄榄辉长岩、浅色橄榄辉长岩、淡色辉长岩(斜长岩)、橄长岩及辉长岩组成,以橄榄辉长岩和橄长岩为主。其主要造岩矿物由斜长石、橄榄石、单斜辉石及少量角闪石组成,具反应边结构和包含嵌晶结构。电子探针分析结果表明,其橄榄石Fo平均为77,属贵橄榄石。单斜辉石全部落入透辉石区。斜长石 An平均为 85,为倍长石。岩相学特征表明,该岩体为典型的堆晶辉长岩体。根据An-Fo及AlZ-TiO2图解可以判别该岩体形成于活动大陆边缘/岛弧的构造环境中,属于 I型弧堆晶辉长岩,其形成可能与古亚洲洋闭合过程中板块俯冲-流体交代作用有关,是研究古亚洲洋闭合历史的一个重要岩石学标志。 | 周长勇 葛文春 吴福元 ABDEL Rahman A A | 2005 | 吉林大学学报(地球科学版)2005，35，2： | 23 |
| 4 | Pancreatits after endoscopic retrograde cholangio-pancreatography显示文摘Pancreatitis is the most common complication after endoscopic retrograde cholangio-pancreatography (ERCP); the reported incidence of this complication varies from less than 1% to 40%, but a rate of 4%-8% is reported in most prospective studies involving non-selected patients. Differences in criteria for defining pancreatitis, methods of data collection, and patient populations (i.e. number of high-risk patients included in the published series) are factors that are likely to affect the varying rates of post-ERCP pancreatitis. The severity of post-ERCP pancreatitis (PEP) can range from a minor inconvenience with one or two days of added hospitalization with full recovery to a devastating illness with pancreatic necrosis, multiorgan failure, permanent disability, and even death. Although, most episodes of PEP are mild (about 90%), a small percentage of patients (about 10%) develop moderate or severe pancreatitis. In the past, PEP was often viewed as an unpredictable and unavoidable complication, with no realistic strategy for its avoidance. New data have aided in stratifi cation of patients into PEP risk categories and new measures have been introduced to decrease the risk of PEP. As most ERCPs are performed on an outpatient basis, the majority of patients will not develop PEP and can be discharged. Alternatively, early detection of those patients who will go on to develop PEP can guide decisions regarding hospital admission and aggressive management. In the last decade, great efforts have been addressed toward prevention of this complication. Points of emphasis have included technical measures, pharmacological prophylaxis, and patient selection. This review provides a comprehensive, evidence-based assessment of published data on PEP and current suggestions for its avoidance. | Ayman M Abdel Aziz Glen A Lehman | 2007 | World Journal of Gastroenterology2007，13，19： | 19 |
| 5 | Seminal plasma anti-Müllerian hormone level correlates with semen parameters but does not predict success of testicular sperm extraction (TESE)显示文摘瞄准:估计精液的血浆 anti-Muellerian 在肥沃、不肥沃的男性的荷尔蒙(AMH ) levalrelationships。方法:84 个男盒子被学习并且把组划分了成四:肥沃的 normozoospermia (n = 16 ) , oligoastheno-teratozoospermia (n = 15 ) ,妨碍的精子缺乏(OA )(n = 13 ) 并且非妨碍的精子缺乏(NOA )(n = 40 ) 。Conventionalsemen 分析为所有情况被做。阴囊的活体检视在 NOA 情况中为阴囊的精子抽取(TESE ) 用完了组织病理学说和新鲜织物检查。NOA 组根据 TESE 结果被细分进失败的 TESE (n = 19 ) 并且成功的 TESE (n = 21 ) 。Seminalplasma AMH 被酶估计连接免疫吸着剂试金(ELISA ) 和浆液小囊的刺激荷尔蒙(FSH ) 仅仅由放射性免疫测定(RIA ) 在 NOA 情况中被估计。结果:Meanseminal AMH 比在有意义的 oligoasthenoteratozoospermia 在肥沃的组是显著地更高的(41.5 ± 10.9 pmol/L 对 30.5 ± 10.3 pmol/L, P <
0.05 ) 。精液的 AMH 没在任何 OA 病人被检测。精液的 AMH 与阴囊的体积断然被相关( r = 0.329 , P =0.005 ),精子计数( r = 0.483 , P = 0.007 ),精子活动性百分比( r = 0.419 , P = 0.021 )并且否定地与精子反常形式百分比( r =-0.413, p = 0.023 )。不重要的关联与年龄是明显的(r =-0.155, P = 0.414 ) 并且血浆 FSH (r =-0.014, P = 0.943 ) 。在 NOA 情况中,精液的 AMH 在 23/40 情况中是可检测的,他们中的 14 个是成功的 TESE (57.5%) 并且在 17/40 情况中是无法发现的,他们中的 10 个是失败的 TESE (58.2%) 。结论:精液的 plasmaAMH 是在所有 OA 盒子中是不在的一个绝对阴囊的标记。然而,精液的 AMH 在 NOA 情况中为成功的阴囊的精子检索有差的可预测性。 | Taymour Mostafa Medhat K. Amer Guirgis Abdel-Malak Taha Abdel Nsser Wael Zohdy Shedeed Ashour Dina El-Gayar Hosam H. Awad | 2007 | Asian Journal of Andrology2007，9，2： | 17 |
| 6 | Ferroptosis:mechanisms and links with diseases显示文摘Ferroptosis is an iron-dependent cell death,which is different from apoptosis,necrosis,autophagy,and other forms of cell death.The process of feroptotic cell death is defined by the accumulation of lethal lipid species derived from the peroxidation of lipids,which can be prevented by iron chelators(e.g.deferiprone,deferoxamine)and small lipophilic antioxidants(e.g,ferrostatin,liproxstatin).This review summarizes current knowledge about the regulatory mechanism of ferroptosis and its association withseveral pathways,including iron,lipid,and cysteine metabolism.We have further discussed the contribution of ferroptosis to thepathogenesis of several diseases such as cancer,ischemia/reperfusion,and various neurodegenerative diseases(e.g.Alzheimersdisease and Parkinson's disease),and evaluated the therapeutic applications of ferroptosis inhibitors in clinics. | Hong-fa Yan Ting Zou Qing-zhang Tuo Shuo Xu Hua Li Abdel Ali Belaidi Peng Lei | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 16 |
| 7 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 8 | Clinicopathological features and surgical outcome of patients with fibrolamellar hepatocellular carcinoma(experience with 22 patients over a 15-year period)显示文摘AIM To evaluate the clinicopathological features and the surgical outcomes of patients with fibrolamellar hepato-cellular carcinoma(FL-HCC)over a 15-year period. METHODS This is a retrospective study including 22 patients with a pathologic diagnosis of FL-HCC who underwent hepatectomy over a 15-year period. Tumor characteristics,survival and recurrence were evaluated. RESULTS There were 11 male and 11 female with a median age of 29 years(range from 21 to 58 years). Two(9%)patients had hepatitis C viral infection and only 2(9%)patients had alpha-fetoprotein level > 200 ng/m L. The median size of the tumors was 12 cm(range from 5-20 cm). Vascular invasion was detected in 5(23%)patients. Four(18%)patients had lymph node metastases. The median follow up period was 42 mo and the 5-year survival was 65%. Five(23%)patients had a recurrent disease,4 of them had a second surgery with 36 mo median time interval. Vascular invasion is the only significant negative prognostic factor CONCLUSION FL-HCC has a favorable prognosis than common HCC and should be suspected in young patients with non cirrhotic liver. Aggressive surgical resection should be done for all patients. Repeated hepatectomy should be considered for these patients as it has a relatively indolent course. | Mohamed Abdel Wahab Ehab El Hanafy Ayman El Nakeeb Mahmoud Abdelwahab Ali | 2017 | World Journal of Gastrointestinal Surgery2017，9，2： | 12 |
| 9 | Single-session minimally invasive management of common bile duct stones显示文摘Up to 18% of patients submitted to cholecystectomy had concomitant common bile duct stones.To avoid serious complications,these stones should be removed.There is no consensus about the ideal management strategy for such patients.Traditionally,open surgery was offered but with the advent of endoscopic retrograde cholangiopancreatography(ERCP) and laparoscopic cholecystectomy(LC) minimally invasive approach had nearly replaced laparotomy because of its well-known advantages.Minimally invasive approach could be done in either twosession(preoperative ERCP followed by LC or LC followed by postoperative ERCP) or single-session(laparoscopic common bile duct exploration or LC with intraoperative ERCP).Most recent studies have found that both options are equivalent regarding safety and efficacy but the singlesession approach is associated with shorter hospital stay,fewer procedures per patient,and less cost.Consequently,single-session option should be offered to patients with cholecysto-choledocholithiaisis provided that local resources and expertise do exist.However,the management strategy should be tailored according to many variables,such as available resources,experience,patient characteristics,clinical presentations,and surgical pathology. | Ahmed Abdel Raouf ElGeidie | 2014 | World Journal of Gastroenterology2014，20，41： | 12 |
| 10 | Elastic properties of chiral,anti-chiral,and hierarchical honeycombs:A simple energy-based approach显示文摘The effects of two geometric refinement strategies widespread in natural structures, chirality and self-similar hierarchy, on the in-plane elastic response of two-dimensional honeycombs were studied systematically. Simple closed-form expressions were derived for the elastic moduli of several chiral, antichiral, and hierarchical honeycombs with hexagon and square based networks. Finite element analysis was employed to validate the analytical estimates of the elastic moduli. The results were also compared with the numerical and experimental data available in the literature. We found that introducing a hierarchical refinement increases the Young's modulus of hexagon based honeycombs while decreases their shear modulus. For square based honeycombs, hierarchy increases the shear modulus while decreasing their Young's modulus. Introducing chirality was shown to always decrease the Young's modulus and Poisson's ratio of the structure. However, chirality remains the only route to auxeticity. In particular, we found that anti-tetra-chiral structures were capable of simultaneously exhibiting anisotropy, auxeticity,and remarkably low shear modulus as the magnitude of the chirality of the unit cell increases. | Davood Mousanezhad Babak Haghpanah Ranajay Ghosh Abdel Magid Hamouda Harold Nayeb-Hashemi Ashkan Vaziri | 2016 | Theoretical & Applied Mechanics Letters2016，6，2： | 11 |
| 11 | Vascular calcification:When should we interfere in chronic kidney disease patients and how?显示文摘Chronic kidney disease(CKD) patients are endangered with the highest mortality rate compared to other chronic diseases. Cardiovascular events account for up to 60% of the fatalities. Cardiovascular calcifications affect most of the CKD patients. Most of this calcification is related to disturbed renal phosphate handling. Fibroblast growth factor 23 and klotho deficiency were incriminated in the pathogenesis of vascular calcification through different mechanisms including their effects on endothelium and arterial wall smooth muscle cells. In addition, deficient klotho gene expression, a constant feature of CKD, promotes vascular pathology and shares in progression of the CKD. The role of gut in the etio-pathogenesis of systemic inflammation and vascular calcification is a newly discovered mechanism. This review will cover the medical history, prevalence, pathogenesis, clinical relevance, different tools used to diagnose, the ideal timing to prevent or to withhold the progression of vascular calcification and the different medications and medical procedures that can help to prolong the survival of CKD patients. | Usama Abdel Azim Sharaf El Din Mona Mansour Salem Dina Ossama Abdulazim | 2016 | World Journal of Nephrology2016，5，5： | 10 |
| 12 | Ground motion spatial variability effects on seismic response control of cable-stayed bridges显示文摘The spatial variability of input ground motion at supporting foundations plays a key role in the structural response of cable-stayed bridges (CSBs); therefore, spatial variation effects should be included in the analysis and design of effective vibration control systems. The control of CSBs represents a challenging and unique problem, with many complexities in modeling, control design and implementation, since the control system should be designed not only to mitigate the dynamic component of the structural response but also to counteract the effects of the pseudo-static component of the response. The spatial variability effects on the feasibility and efficiency of seismic control systems for the vibration control of CSBs are investigated in this paper. The assumption of uniform earthquake motion along the entire bridge may result in quantitative and qualitative differences in seismic response as compared with those produced by uniform motion at all supports. A systematic comparison of passive and active system performance in reducing the structural responses is performed, focusing on the effect of the spatially varying earthquake ground motion on the seismic response of a benchmark CSB model with different control strategies, and demonstrates the importance of accounting for the spatial variability of excitations. | Shehata E. Abdel Raheem Toshiro Hayashikawa Uwe Dorka | 2011 | Earthquake Engineering and Engineering Vibration2011，10，1： | 9 |
| 13 | 埃及尼罗河三角洲城市化监测显示文摘对1972、1984和1990年在尼罗河三角洲获取的Landsat MSS和TM影象(scenes)处理的和协同配准的(coregistered)数字镶嵌图比较表明,城镇增长正危及着埃及农业的生产力。在1972、1984和1990年尼罗河三角洲的城镇面积至少分别占3.6%、4.7%和5.7%,在这18年期间增长了58%。大约一半的增长出现在1984~1990年期间。如果这种趋势继续下去,到2010年埃及将因城市化而丧失农地总面积的12%。尽管事实上城镇增长主要出现在城市周围,但在几千个小村庄周围的增长却对尼罗河三角洲的农业生产构成最大的威胁。1972~1990年间,城市和大村庄的累积增长率为37%,而同期小村庄的累积增长率为77%。 | Mohamed Sultan Michael Fiske Thomas Stein Mohamed Gamal Yehia Abdel Hady Hesham El Araby Ahmed Madani Salah Mehanee Richard Becker 石培礼 | 1999 | AMBIO-人类环境杂志1999，28，7： | 9 |
| 14 | Updates in the pathophysiological mechanisms of Parkinson's disease: Emerging role of bone marrow mesenchymal stem cells显示文摘AIM: To explore the approaches exerted by mesenchymal stem cells(MSCs) to improve Parkinson's disease(PD) pathophysiology.METHODS: MSCs were harvested from bone marrowof femoral bones of male rats, grown and propagated in culture. Twenty four ovariectomized animals were classified into 3 groups: Group(1) was control, Groups(2) and(3) were subcutaneously administered with rotenone for 14 d after one month of ovariectomy for induction of PD. Then, Group(2) was left untreated, while Group(3) was treated with single intravenous dose of bone marrow derived MSCs(BM-MSCs). SRY gene was assessed by PCR in brain tissue of the female rats. Serum transforming growth factor beta-1(TGF-β1), monocyte chemoattractant protein-1(MCP-1) and brain derived neurotrophic factor(BDNF) levels were assayed by ELISA. Brain dopamine DA level was assayed fluorometrically, while brain tyrosine hydroxylase(TH) and nestin gene expression were detected by semi-quantitative real time PCR. Brain survivin expression was determined by immunohistochemical procedure. Histopathological investigation of brain tissues was also done.RESULTS: BM-MSCs were able to home at the injured brains and elicited significant decrease in serum TGF-β1(489.7 ± 13.0 vs 691.2 ± 8.0, P < 0.05) and MCP-1(89.6 ± 2.0 vs 112.1 ± 1.9, P < 0.05) levels associated with significant increase in serum BDNF(3663 ± 17.8 vs 2905 ± 72.9, P < 0.05) and brain DA(874 ± 15.0 vs 599 ± 9.8, P < 0.05) levels as well as brain TH(1.18 ± 0.004 vs 0.54 ± 0.009, P < 0.05) and nestin(1.29 ± 0.005 vs 0.67 ± 0.006, P < 0.05) genes expression levels. In addition to, producing insignificant increase in the number of positive cells for survivin(293.2 ± 15.9 vs 271.5 ± 15.9, P > 0.05) expression. Finally, the brain sections showed intact histological structure of the striatum as a result of treatment with BM-MSCs. CONCLUSION: The current study sheds light on the therapeutic potential of BM-MSCs against PD pathophysiology via multi-mechanistic actions. | Hanaa H Ahmed Ahmed M Salem Hazem M Atta Emad F Eskandar Abdel Razik H Farrag Mohamed A Ghazy Neveen A Salem Hadeer A Aglan | 2016 | World Journal of Stem Cells2016，8，3： | 9 |
| 15 | IL28B polymorphism and cytomegalovirus predict response to treatment in Egyptian HCV type 4 patients显示文摘AIM:To test whether the status of positive cytomegalovirus(CMV) DNA detection adds to the predictive value of IL28B and to further categorize C/T allele carriers.METHODS:This study included 166 chronic hepatitis C(CHC) patients who received combined interferon and ribavirin therapy for 48 wk,84 spontaneous hepatitis C virus(HCV) resolvers who were positive for IgG anti-HCV antibody and negative for HCV RNA,and 100 healthy subjects who were negative for both HCV antibodies and RNA as controls.Genomic DNA from peripheral blood was used for IL28B rs.12979860 single nucleotide polymorphism(SNP) and CMV DNA detection.A 139 bp fragment containing IL28B SNP was amplified in all subjects by polymerase chain reaction using a specifically designed primer.Then the IL28B rs.12979860 SNP was detected by restriction fragment length polymorphism(RFLP) genotyping.The presence of CMV DNA was tested by amplification of the gB1 gene using nested polymerase chain reaction.The role of CMV and IL28B rs.12979860 SNP genotypes in determining the response rate to combined interferon therapy and clinical status of patients were statistically analyzed.RESULTS:Current data showed that 67% of patients carrying the IL28B 12979860 C/C allele had a sustained viral response(SVR) while the genotypes C/T and TT were associated with lower SVR rates,50% and 48%,respectively.SVR rates for the C/C allele were lower than other HCV genotypes and/or other populations.Genotype CC was associated with the response to interferon(P = 0.025).Genotype C/C was reduced from 48% in controls to 14% in CHC patients suggesting its protective role against progression to chronicity.The majority of spontaneously cleared subjects(86%) were C/C,confirming its protective role.The C/T allele was present in 71% of CHC patients compared with 38% of controls,so the use of IL28B SNP genotyping only in these patients may be of little value as a predictor of response.CMV reactivation occurred in 40% of CHC patients.Co-infection with CMV seriously diminished the response to interferon(IFN) therapy,with SVR rates in C/C genotypes 87.5% in CMV-negative patients and 12.5% in CMV-positive patients(P < 0.0001).SVR rates among C/T carriers were reduced to < 50% in patients with positive CMV DNA while the non-response rate doubled.These data indicate that a supplemental assay for CMV viremia adds to the prognostic value of IL28B genotyping.CONCLUSION:The results suggest that both genetic(i.e.,spontaneous) and therapeutic(IFN-based therapy) arms are complementary in the battle against HCV.CMV DNA testing may be of value to better predict the response to IFN,particularly in IL28B C/T carriers. | Mostafa K El Awady Noha G Bader El Din Ashraf Tabll Yaser El Hosary Ashraf O Abdel Aziz Hesham El Khayat Mohsen Salama Tawfeek H Abdelhafez | 2013 | World Journal of Gastroenterology2013，19，2： | 8 |
| 16 | Pancreatic injury in patients with septic shock: A literature review显示文摘Sepsis and septic shock are life threatening condition associated with high mortality rate in critically-ill patients. This high mortality is mainly related to the inadequacy between oxygen delivery and cellular demand leading to the onset of multiorgan dysfunction. Whether this multiorgan failure affect the pancreas is not fully investigated. In fact, pancreatic injury may occur because of ischemia, overwhelming inflammatory response, oxidative stress, cellular apoptosis and/or metabolic derangement. Increased serum amylase and/or lipase levels are common in patients with septic shock. However, imaging test rarely reveal significant pancreatic damage. Whether pancreatic dysfunction does affect the prognosis of patients with septic shock or not is still a matter of debate. In fact, only few studies with limited sample size assessed the clinical relevance of the pancreatic injury in this group of patients. In this review, we aimed to describe the epidemiology and the physiopathology of pancreatic injury in septic shock patients, to clarify whether it requires specific management and to assess its prognostic value. Our main finding is that pancreatic injury does not significantly affect the outcome in septic shock patients. Hence, increased serum pancreatic enzymes without clinical features of acute pancreatitis do not require further imaging investigations and specific therapeutic intervention. | Anis Chaari Karim Abdel Hakim Kamel Bousselmi Mahmoud Etman Mohamed El Bahr Ahmed El Saka Eman Hamza Mohamed Ismail Elsayed Mahmoud Khalil Vipin Kauts William Francis Casey | 2016 | World Journal of Gastrointestinal Oncology2016，8，7： | 8 |
| 17 | Stop chronic kidney disease progression: Time is approaching显示文摘Progression of chronic kidney disease(CKD) is inevitable. However, the last decade has witnessed tremendous achievements in this field. Today we are optimistic; the dream of withholding this progression is about to be realistic. The recent discoveries in the field of CKD management involved most of the individual diseases leading the patients to end-stage renal disease. Most of these advances involved patients suffering diabetic kidney disease, chronic glomerulonephritis, polycystic kidney disease, renal amyloidosis and chronic tubulointerstitial disease. The chronic systemic inflammatory status and increased oxidative stress were also investigated. This inflammatory status influences the antisenescence Klotho gene expression. The role of Klotho in CKD progression together with its therapeutic value are explored. The role of gut as a major source of inflammation, the pathogenesis of intestinal mucosal barrier damage, the role of intestinal alkaline phosphatase and the dietary and therapeutic implications add a novel therapeutic tool to delay CKD progression. | Usama Abdel Azim Sharaf El Din Mona Mansour Salem Dina Ossama Abdulazim | 2016 | World Journal of Nephrology2016，5，3： | 6 |
| 18 | Robotic nurse duties in the urology operative room:11 years of experience显示文摘The robotic nurse plays an essential role in a successful robotic surgery.As part of the robotic surgical team,the robotic nurse must demonstrate a high level of professional knowledge,and be an expert in robotic technology and dealing with robotic malfunctions.Each one of the robotic nursing team“nurse coordinator,scrub-nurse and circulating-nurse”has a certain job description to ensure maximum patient’s safety and robotic surgical efficiency.Well-structured training programs should be offered to the robotic nurse to be well prepared,feel confident,and maintain high-quality of care. | Ali Abdel Raheem Hyun Jung Song Ki Don Chang Young Deuk Choi Koon Ho Rha | 2017 | Asian Journal of Urology2017，4，2： | 6 |
| 19 | Combining Committee-Based Semi-Supervised Learning and Active Learning显示文摘Many data mining applications have a large amount of data but labeling data is usually difficult,expensive,or time consuming,as it requires human experts for annotation.Semi-supervised learning addresses this problem by using unlabeled data together with labeled data in the training process.Co-Training is a popular semi-supervised learning algorithm that has the assumptions that each example is represented by multiple sets of features(views) and these views are sufficient for learning and independent given the class.However,these assumptions are strong and are not satisfied in many real-world domains.In this paper,a single-view variant of Co-Training,called Co-Training by Committee(CoBC) is proposed,in which an ensemble of diverse classifiers is used instead of redundant and independent views.We introduce a new labeling confidence measure for unlabeled examples based on estimating the local accuracy of the committee members on its neighborhood.Then we introduce two new learning algorithms,QBC-then-CoBC and QBC-with-CoBC,which combine the merits of committee-based semi-supervised learning and active learning.The random subspace method is applied on both C4.5 decision trees and 1-nearest neighbor classifiers to construct the diverse ensembles used for semi-supervised learning and active learning.Experiments show that these two combinations can outperform other non committee-based ones. | Mohamed Farouk Abdel Hady Friedhelm Schwenker | 2010 | Journal of Computer Science & Technology2010，25，4： | 5 |
| 20 | 为恶意、良性的胆汁的苛评的治疗的充分盖住的自我可扩充的金属 stents显示文摘 AIM:To present a series of covered self-expandable metal stents(CSEMS) placed for different indications and to evaluate the effectiveness,complications and extractability of these devices.METHODS:We therefore retrospectively reviewed the courses of patients who received CSEMS due to malignant as well as benign biliary strictures and postsphincterotomy bleeding in our endoscopic unit between January 2010 and October 2011.RESULTS:Twenty-six patients received 28 stents due to different indications(20 stents due to malignant biliary strictures,six stents due to benign biliary strictures and two stents due to post-sphincterotomy bleeding).Biliary obstruction was relieved in all cases,regardless of the underlying cause.Hemostasis could be achieved in the two patients who received the stents for this purpose.Complications occurred in five patients(18%).Two patients(7%) developed cholecystitis,stents dislocated/migrated in other two patients(7%),and in one patient(3.6%) stent occlusion was documented during the study period.Seven stents were extracted endoscopically.Removal of stents was easily possible in all cases in which it was desired using standard forceps.Twelve patients underwent surgery with pylorus preserving duodenopancreatectomy.In all patients stents could be removed during the operation without difficulties.CONCLUSION:Despite the higher costs of these devices,fully covered self-expanding metal stents may be suitable to relief biliary obstruction due to bile duct stenosis,regardless of the underlying cause.CSEMS may also represent an effective treatment strategy of severe post-sphincterotomy bleeding,not controlled by other measures. | Ahmed Abdel Samie Stephan Dette Ulrich Vhringer Michael Stumpf Karolin Kopischke Lorenz Theilmann | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 5 |
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