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| 1 | Impacts of common factors of life style on serum liver enzymes显示文摘AIM: To investigate the impacts of gender, age and factors of life style(alcohol, overweight, coffee and smoking) on serum liver enzymes.METHODS: Serum alanine aminotransferase(ALT) and gamma-glutamyltransferase(GGT) were measured from 6269 apparently healthy individuals(2851 men, 3418 women, mean age 45 ± 12 years, range 25-74 years) in a national cross-sectional health survey. All subjects underwent detailed clinical examinations and interviews including the amount and pattern of alcoholuse, coffee consumption and smoking habits. RESULTS: In this population with a mean ± SD alcohol consumption of 65 ± 105 g/wk and body mass index(BMI) of 26.1 ± 4.3 kg/m2, both ALT and GGT were significantly influenced by alcohol use(P < 0.001) and BMI(P < 0.001), whereas smoking increased only GGT(P < 0.001). A significant effect of age on ALT was seen in men(P < 0.001) whereas not in women. Significant two-factor interactions of alcohol use in men were observed with age(ALT: P < 0.01; GGT: P < 0.001) and BMI(GGT: P < 0.05). For ALT, a significant interaction also occurred between BMI and age(P < 0.005). In contrast, women showed significant interactions of alcohol use with BMI(GGT: P < 0.05), smoking(GGT: P < 0.001), and coffee consumption(GGT: P < 0.001). CONCLUSION: Life-style associated changes in liver enzymes may reflect health risks, which should be considered in the definition of normal limits for liver enzymes. | Joanna Danielsson Pivikki Kangastupa Tiina Laatikainen Mauri Aalto Onni Niemel | 2014 | World Journal of Gastroenterology2014，20，33： | 2 |
| 2 | Observations of ultrafine aerosol particle formation and growth in boreal forest 显示文摘 | M?kel? J M Aalto P Jokinen V | 1997 | Geophysical Research Letters1997，24，10： | 1 |
| 3 | Semi-continuous gas and inorganic aerosol measurements at a Finnish urban site: comparisons with filters, nitrogen in aerosol and gas phases, and aerosol acidity显示文摘 | Makkonen U. Virkkula A. M?ntykentt? J. Hakola H. Keronen P. Vakkari V. Aalto P. P | 2012 | Atmospheric Chemistry and Physics2012，，272： | 1 |
| 4 | Large-scale production of dsRNA and siRNA pools for RNA interference utilizing bacteriophage phi6 RNA-dependent RNA polymerase显示文摘 | SARIN L P VAN DIJK A A | 2007 | RNA2007，13，3： | 1 |
| 5 | Correlation of lateralstenosis in MRI with symptoms,walking capacity and EMGfindings in patients with surgically confirmed lateral lumbar spinalcanal stenosis显示文摘 | Kuittinen P Sipola P Aalto TJ | 2014 | BMC Musculoskelet Disord2014，15，： | 1 |
| 6 | Msx1 gene is deleted in Wolf-Hirschhorn Syndrome patients with oligodontia显示文摘 | Nieminen P Kotilainen J Aalto Y | 2003 | J Dent Res2003，82，12： | 1 |
| 7 | Type 2 diabetes whole- genome association study in four populations: the DiaGen consor- tium 显示文摘 | Salonen JT Uimari P Aalto JM | 2007 | Am J Hum Genet2007，81，2： | 1 |
| 8 | Simultaneous determination of bromhexine hydrochloride and methyl and propyl p-hydroxybenzoate and determination of dextromethorphan hydrobromide in cough-cold syrup by high performance liquid chromatography显示文摘 | RAUHA J P SALOMIES H AALTO M | 1996 | J Pharm Biomed Anal1996，15，2： | 1 |
| 9 | Type 2 diabetes whole-genome association study in four populations:the DiaGen consortium显示文摘 | Salonen JT Uimari P Aalto JM | 2007 | Am J Hum Genet2007，81，2： | 1 |
| 10 | Impaired cognitive performance in Parkinson's disease is related to caudate dopaminergic hypofunction and hippocampal atrophy显示文摘 | Jokinen P Bruck A Aalto S | | 0，，02： | 1 |
| 11 | Observations of ultrafine aerosol particle formation and growth in boreal forest 显示文摘 | Makela J M Aalto P Jokinen V | 1997 | Geophysical Research Letters1997，24，10： | 1 |
| 12 | Overview of the international project on biogenic aerosol formation in the boreal forest显示文摘 | Kulmala M Hameri K Aalto P | 2001 | Chemical meteorology2001，53，7： | 1 |
| 13 | BIood flow in rabbit osteotomies studied with radioactive microspheresm显示文摘 | Aalto K SIatis P | 1984 | Acta Orthop Scamd1984，55，6： | 1 |
| 14 | PIB-,FDG-PET and MRI imaging in patients with Parkinson's disease with and without dementia显示文摘 | Jokinen P Scheinin N Aalto S | 2010 | Parkinsonism Relat Disord2010，16，10： | 1 |
| 15 | Measrtfing patient assessments of the quality of outpatient care: a systematic review显示文摘 | Saila T Mattila E Kaila M Aalto P Kaunonen M | | J Eval Clin Pract0，14，1： | 1 |
| 16 | Postural control in elderly sub- jects显示文摘 | Pyykko I Jantti P Aalto H | 1990 | Age Ageing1990，19，3： | 1 |
| 17 | Associations of traffic rela- ted air pollutants with hospitalisation for first acute myoeardial in- farction: the HEAPSS study显示文摘 | Lanki T Pekkanen J Aalto P | 2006 | Oceup Environ Med2006，63，12： | 1 |
| 18 | Ambient air pollution is associated with increased risk of hospital cardiac readmissions of myocardial infarction survivors in five European cities显示文摘 | yon Klot S Peters A Aalto P | 2005 | Circu- lation2005，112，20： | 1 |
| 19 | Nerve growth factor in serum of children with systemic lupus erythematosus is correlated with disease activity显示文摘 | Aalto K Korhonen L Lahdenne P | 2002 | Cytokine2002，20，3： | 1 |
| 20 | PIB, FDG-PET and MRI imaging in patients with Parkinson' s disease with and without dementia 显示文摘 | Jokinen P Scheinin N Aalto S | 2010 | Parkinsonism Relat Disord2010，16，10： | 1 |
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