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| 1 | Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention显示文摘AIM:To assess pediatric patients for choledocholithiasis.We applied current adult guidelines to identify predictivefactors in children.METHODS:A single-center retrospective analysis was performed at a tertiary children's hospital.We evaluated 44 consecutive pediatric patients who underwent endoscopic retrograde cholangiography(ERCP) for suspected choledocholithiasis.Patients were stratified into those with common bile duct stones(CBDS) at ERCP vs those that did not using the American Society of Gastrointestinal Endoscopy(ASGE) guidelines(Very Strong and Strong criteria) for suspected CBDS.RESULTS:CBDS were identified in 84% at the time of ERCP.Abdominal ultrasound identified CBDS in 36% of patients.Conjugated bilirubin ≥ 0.5 mg/d L was an independent risk factor for CBDS(P = 0.003).The Very Strong(59.5%) and Strong(48.6%) ASGE criteria identified the majority of patients(P = 0.0001).A modified score using conjugated bilirubin had a higher sensitivity(81.2% vs 59.5%) and more likely to identify a stone than the standard criteria,odds ratio of 25.7 compared to 8.8.Alanine aminotransferase and gamma-glutamyl transferase values identified significant differences in a subset of patients with odds ratio of 4.1 and 3.25,respectively.CONCLUSION:Current adult guidelines identified the majority of pediatric patients with CBDS,but specific pediatric guidelines may improve detection,thus decreasing risks and unnecessary procedures. | Douglas S Fishman Bruno P Chumpitazi Isaac Raijman Cynthia Man-Wai Tsai E O’Brian Smith Mark V Mazziotti Mark A Gilger | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，11： | 6 |
| 2 | Esophageal tissue engineering:A new approach for esophageal replacement显示文摘A number of congenital and acquired disorders require esophageal tissue replacement.Various surgical techniques,such as gastric and colonic interposition,are standards of treatment,but frequently complicated by stenosis and other problems.Regenerative medicine approaches facilitate the use of biological constructs to replace or regenerate normal tissue function.We review the literature of esophageal tissue engineering,discuss its implications,compare the methodologies that have been employed and suggest possible directions for the future.Medline,Embase,the Cochrane Library,National Research Register and ClinicalTrials.gov databases were searched with the following search terms:stem cell and esophagus,esophageal replacement,esophageal tissue engineering,esophageal substitution.Reference lists of papers identified were also examined and experts in this field contacted for further information.All full-text articles in English of all potentially relevant abstracts were reviewed.Tissue engineering has involved acellular scaffolds that were either transplanted with the aim of being repopulated by host cells or seeded prior to transplantation.When acellular scaffolds were used to replace patch and short tubular defects they allowed epithelial and partial muscular migration whereas when employed for long tubular defects the results were poor leading to an increased rate of stenosis and mortality.Stenting has been shown as an effective means to reduce stenotic changes and promote cell migration,whilst omental wrapping to induce vascularization of the construct has an uncertain benefit.Decellularized matrices have been recently suggested as the optimal choice for scaffolds,but smart polymers that will incorporate signalling to promote cell-scaffold interaction may provide a more reproducible and available solution.Results in animal models that have used seeded scaffolds strongly suggest that seeding of both muscle and epithelial cells on scaffolds prior to implantation is a prerequisite for complete esophageal replacement.Novel approaches need to be designed to allow for peristalsis and vascularization in the engineered esophagus.Although esophageal tissue engineering potentially offers a real alternative to conventional treatments for severe esophageal disease,important barriers remain that need to be addressed. | Giorgia Totonelli Panagiotis Maghsoudlou Jonathan M Fishman Giuseppe Orlando Tahera Ansari Paul Sibbons Martin A Birchall Agostino Pierro Simon Eaton Paolo De Coppi | 2012 | World Journal of Gastroenterology2012，18，47： | 5 |
| 3 | The value of transvaginal sonography in the preoperative assessment of myometrial invasion in high and low grade endometrial cancer and in comparison to frozen section in grade 1disease 显示文摘 | Altaras M Bernheim J | 2000 | Eur J Gynaecol Oncol2000，21，： | 1 |
| 4 | Selective performance of prophylactc omentopexy during laparoscopic implantation of peritoneal dialysis catheters显示文摘 | Crabtree JH Fishman A | 2003 | Surg Laparosc Endosc Percutan Tech2003，13，3： | 1 |
| 5 | Prevention and management of cerebrospinal fluid leak following vestibular schwannoma surgery 显示文摘 | Fishman A J Marrinan MS Golfinos JG | 2004 | Laryngoscope2004，114，3： | 1 |
| 6 | The value of transvaginal sonography in the preoperative assessment of myomeyrial invasion in high and lowgrade endometrial cancer and in comparison to frozen section in grade 1 disease显示文摘 | Fishman A Altaras M Bemheim j | 2000 | Eur j Gynaecol Oneo2000，21，1： | 1 |
| 7 | Differentiation of human embryonic stem cells into insulin-producing clusters显示文摘 | Segev H Fishman B Ziskind A | 2004 | Stem Cells2004，22，3： | 1 |
| 8 | Metalworking Method for Composites 显示文摘 | Diveeha A P Fishman S G Karmalkal S D | 1981 | J Metals1981，33，： | 1 |
| 9 | A laparoscopic method for optimal peritoneal dialysis access 显示文摘 | Crabtree JH Fishman A | 2005 | Am Surg2005，71，2： | 1 |
| 10 | Whorfianism of the third kind: ethnolinguistic diversity as a worldwide societal asset显示文摘 | Fishman Joshua A | 1982 | Language in Society1982，，11： | 1 |
| 11 | The nature of porosity in organic-rich mudstones of the Upper Jurassic Kimmeridge Clay Formation, North Seam offshore United Kingdom显示文摘 | Fishman N S Haekley P C Lowers H A | 2012 | International Journal of Coal Geology2012，103，： | 1 |
| 12 | Protection of ovarian function and fertility using a combination of gonadotropin-releasing hormone (GnRH) agonist and GnRH antagonist during cancer treatment in young females显示文摘 | Fishman A Coben I | 2007 | Gynecol Endocrinol2007，23，5： | 1 |
| 13 | Combination antiviral therapy for ganciclovir-resistant cytomegalovirus infection in solidorgan transplant recipients显示文摘 | MYLONAKIS E KALLAS W M FISHMAN J A | 2002 | Clin Infect Dis2002，34，： | 1 |
| 14 | CT evaluation of small bowel neo- plasms: spectrum of disease显示文摘 | Buckley J A Fishman E K | 1998 | Radiographics1998，18，2： | 1 |
| 15 | NK cells, innate immunity and hepatitis C infection after liver transplantation显示文摘 | Anoma N Fishman A | 2011 | J Clin Infect Dis2011，52，3： | 1 |
| 16 | A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema显示文摘 | Fishman A Martinez F Naunheim K | 2003 | N Engl J Med2003，348，21： | 1 |
| 17 | Neural stimulation with a carbon nanotube microelectrode array 显示文摘 | Wang K Fishman H A Dai H J | 2006 | Nano Letters2006，6，9： | 1 |
| 18 | Long-term follow- up of postmenopausal breastcancer patients following discontin uationof tamoxifen therapy显示文摘 | Markovitch O Tepper R Fishman A | 2008 | Maturitas2008，59，4： | 1 |
| 19 | The nature of porosity in or- ganic-rich mudstones of the Upper Jurassic Kimmeridge Clay Formation, North Sea, offshore United Kingdom显示文摘 | Fishman N S Hackley P C Lowers H A Hill R J Egenhoff S O Eberl D D Blum A E | 2012 | Int J Coal Geol2012，7，12： | 1 |
| 20 | Cerebrospinal fluid drainage in the management of CSF leak following acoustic neuroma surgery显示文摘 | HOFFMAN R A ROLAND J | 1996 | Laryngoscope1996，106，8： | 1 |
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