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3416篇 您的检索式:期刊名="Drug Metab Dispos"
    题名 作者 年代 出处 被引量
1Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator显示文摘TUVESSON H HALLIN I PERSSON R 2005Drug Metab Dispos2005,33,6:1
2Absorption,distribution and elimination of tea polyphenols in rats显示文摘Chen L S Lee M J Li H 1997Drug Metab Dispos1997,25,9:1
3Metabolism and disposition of the antihypertensive agent moxonidine in humans 显示文摘He MM Abraham TL Lindsay TJ 2003Drug Metab Dispos2003,31,3:1
4Metebolism and excretion of atorvastatin in rats and dogs显示文摘 Hayes RN Roth BD 1999Drug Metab Dispos1999,27,8:1
5Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation显示文摘Henriette E Meyer zu Schwabedissen Jedlitschky G 2005Drug Metab Dispos2005,33,7:1
6Modeling, prediction, and in vitro in vivo correlation of CYP3A4 induction显示文摘Shou M Hayashi M Pan Y 2008Drug Metab Dispos2008,36,11:1
7A natural variant of the heme-binding signature (R441C) re- sulting in complete loss of function of CYP2D6显示文摘Klein K Tatzei S Raimundo S 2007Drug Metab Dispos2007,35,8:1
8In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors 显示文摘Tang J Akao T Nakamura N 2007Drug Metab Dispos2007,35,10:1
9Stereoselective metabolism of lansoprazole by human liver cytochrome p450 enzymes显示文摘Kim KA kim MJ park JY 2003Drug Metab Dispos2003,31,10:1
10Regulation of CYP3A4 expression in human hepatocytes by pharmaceuticals and natural products 显示文摘Raucy JL 2003Drug Metab Dispos2003,31,:1
11CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers 显示文摘Donato MT Viitala P Rodriguez-Antona C 2000Drug Metab Dispos2000,28,11:1
12Deuterium isotope effect on the toxicokinetics of monomethylamine in the rat显示文摘Streeter AJ Nims RW Sheffels PR Hrabie JA Ohannesian L Heur YH 1990Drug Metab Dispos1990,18,4:1
13Acetaminophen-induced hepatotoxicity显示文摘James LP Mayeux PR Hinson JA 2003Drug Metab Dispos2003,31,12:1
14Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects显示文摘PATRICK J E KOSOGLOU T STAUBER K L 2002Drug Metab Dispos2002,30,4:1
15Ethoxyresorufin:direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene显示文摘BURKE M D MAYER R T 1974Drug Metab Dispos1974,,2:1
16Comparison of fresh and cryopreserved rat hepatocyte suspensions for the prediction of in vitro intrinsic clearance显示文摘GRIFFIN SJ HOUSTON JB 2004Drug Metab Dispos2004,32,5:1
17P450 enzyme expression patterns in the NCI human tumor cell line panel显示文摘Yu LJ Matias J Scudiero DA 2001Drug Metab Dispos2001,29,3:1
18Comparison of inhibitory effects of the proton pump-inhibiting drugs Omeprazole, Lansoprazole, Pantoprazole, Esomeprazole and Rabeprazole on human cytochrome P450 activities显示文摘Li XQ Andersson TB Weidolf L 2004Drug Metab Dispos2004,32,:1
19Evaluation of cyto- chrome P450 probe substrates commonly used by the pharmaceu- tical industry to study in vitro drug interactions 显示文摘Yuan R Madani S Wei X X 2002Drug Metab Dispos2002,30,12:1
20Magnesium Lithospermate B is extracted rapidly into rat bile mostly as methylated metabolites,which are potent antioxidants显示文摘Zhang Y Akao T Nakamura N 2004Drug Metab Dispos2004,32,7:1
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